Enteropathic Arthritis
78 Enteropathic Arthritis Frank A. Wollheim, Monika Ronneberger Key Points The gut wall is a leaky barrier exposed to commensal and pathogenic microorganisms. Microbiota are essential for maturation and regulation…
Shoulder Pain
46 Shoulder Pain Scott David Martin, Thomas S. Thornhill Key Points Comprehension of functional anatomy allows diagnosis of most causes of shoulder pain on clinical examination. History and clinical examination…
Etiology and Pathogenesis of Hyperuricemia and Gout
94 Etiology and Pathogenesis of Hyperuricemia and Gout Robert T. Keenan, Johannes Nowatzky, Michael H. Pillinger Key Points Uric acid is the biologically active end product of human purine metabolism….
Overlap Syndromes
86 Overlap Syndromes Robert Bennett Key Points Diffuse connective tissue diseases are usually associated with autoimmunity to spliceosomal components (U-RNPs, heterogeneous RNPs), nucleosomal components (nucleosomes, DNA, histones), and proteosomal components…
Treatment of Rheumatoid Arthritis
71 Treatment of Rheumatoid Arthritis James R. O’Dell Key Points Diagnose rheumatoid arthritis (RA) early and initiate disease-modifying antirheumatic drug (DMARD) therapy at the time of diagnosis. Treat all patients…
Etiology and Pathogenesis of Rheumatoid Arthritis
69 Etiology and Pathogenesis of Rheumatoid Arthritis Gary S. Firestein Key Points Rheumatoid arthritis (RA) is a complex disease involving numerous cell types, including macrophages, T cells, B cells, fibroblasts,…
Antineutrophil Cytoplasm Antibody–Associated Vasculitis
89 Antineutrophil Cytoplasm Antibody–Associated Vasculitis Caroline O.S. Savage, Lorraine Harper Key Points Granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and allergic granulomatosis with polyangiitis (AGPA) are forms of vasculitis that…
Psoriatic Arthritis
77 Psoriatic Arthritis Oliver Fitzgerald Key Points Psoriatic arthritis should be suspected in a patient with an asymmetric joint distribution pattern who may have additional clinical features, such as dactylitis,…
The Skin and Rheumatic Diseases
43 The Skin and Rheumatic Diseases Lela A. Lee, Victoria P. Werth Key Points Many systemic rheumatologic conditions present with skin findings. The differential diagnosis for skin findings may require…
Biomechanics
6 Biomechanics Kenton R. Kaufman, Kai-Nan An Key Points Kinematics is the study of the geometric and time-dependent aspects of motion without analyzing the forces causing the motion. The general…
