70 Clinical Features of Rheumatoid Arthritis Susan E. Sweeney, Edward D. Harris, Jr., Gary S. Firestein Key Points Rheumatoid arthritis is a symmetric inflammatory polyartciular arthritis that mainly affects the…
58 Imaging Modalities in Rheumatic Diseases Mikkel Østergaard, Robert G.W. Lambert, Walter Grassi Key Points Practical Use of Imaging in Inflammatory Joint Diseases A. Peripheral joints Use in clinical practice:…
48 Hip and Knee Pain James I. Huddleston, Stuart Goodman Key Points The clinician should be able to narrow the differential diagnosis of hip or knee pain down to two…
97 Familial Autoinflammatory Syndromes Anna Simon, Jos W.M. van der Meer, Joost P.H. Drenth Key Points Autoinflammatory disorders are characterized by recurrent or chronic inflammation without signs of infection or…
84 Clinical Features and Treatment of Scleroderma Francesco Boin, Fredrick M. Wigley Key Points Systemic sclerosis is a multisystem connective tissue disease affecting the skin and internal organs. The disease…
53 Synovial Fluid Analyses, Synovial Biopsy, and Synovial Pathology Hani S. El-Gabalawy Key Points Analysis of synovial fluid samples by leukocyte count, cytology, polarized microscopy, Gram stain, and culture provides…
21 Genetics of Rheumatic Diseases Peter K. Gregersen Key Points HLA molecules are among the most highly variable (polymorphic) proteins encoded in the genome. HLA variability is a major factor…
103 Osteonecrosis Christopher Chang, Adam Greenspan, M. Eric Gershwin Key Points Osteonecrosis affects younger patients more often than osteoarthritis and has significantly greater long-term morbidity. Corticosteroids constitute the most common…
96 Calcium Crystal Disease Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate Robert Terkeltaub Key Points Dysregulated chondrocyte differentiation to hypertrophy and inorganic pyrophosphate (PPi) metabolism are central in pathogenesis of…
85 Inflammatory Diseases of Muscle and Other Myopathies Kanneboyina Nagaraju, Ingrid E. Lundberg Key Points Myopathies are a heterogeneous group of muscle diseases characterized by symmetric proximal muscle weakness and…
