Gout and the Heart

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Gout and the Heart

The association between gout and cardiovascular diseases has been noted for centuries but was not subjected to rigorous epidemiologic studies until recently. The published literature is almost unanimous in the…

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Systemic Sclerosis and the Heart

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Systemic Sclerosis and the Heart

Heart disease, either clinically apparent or silent, is a frequent complication of systemic sclerosis (SSc, scleroderma) and may affect both patients with diffuse cutaneous and limited cutaneous SSc. The availability…

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The Heart and Pediatric Rheumatology

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on The Heart and Pediatric Rheumatology

Recent advances in Kawasaki disease have included attempts to define genes involved in its pathogenesis. There have been recent advances in the studies of rheumatic carditis, leading to a better…

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Cardiac Manifestations of Systemic Lupus Erythematosus

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Cardiac Manifestations of Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that manifests with multiorgan inflammation. Cardiac involvement is common, with manifestation that include pericarditis, myocarditis, conduction defects, valvular disease, and coronary…

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Cardiovascular Disease in Rheumatoid Arthritis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Cardiovascular Disease in Rheumatoid Arthritis

Cardiovascular disease causes significant morbidity and mortality in rheumatoid arthritis (RA). Accelerated atherosclerosis caused by inflammation is the hallmark of cardiovascular disease in RA. Cardiac involvement as an extra-articular manifestation…

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The Heart in Vasculitis

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on The Heart in Vasculitis

Any cardiac tissue can be affected in most primary vasculitides. However, certain entities such as eosinophilic granulomatosis with polyangiitis (or Churg-Strauss syndrome) and Takayasu arteritis involve the heart in up…

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The Heart in Inflammatory Myopathies

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on The Heart in Inflammatory Myopathies

Cardiac involvement in the idiopathic inflammatory myopathies (IIM) has been reported in 5% to 70% of cases. It is estimated that between 15% and 55% of deaths are related to…

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Emerging Therapies for Gout

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Emerging Therapies for Gout

Over the past decade much has been learned about the mechanisms of crystal-induced inflammation and renal excretion of uric acid, which has led to more specific targeting of gout therapies…

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Long-Term Management of Gout

Sep 28, 2017 by in RHEUMATOLOGY Comments Off on Long-Term Management of Gout

Gout is a common disorder with clinical signs and symptoms resulting from inflammatory responses to monosodium urate crystals deposited in tissues from extracellular fluids saturated for urate. Long-term management of…

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