Analgesic Agents in Rheumatic Disease
66 Analgesic Agents in Rheumatic Disease Gregory R. Polston, Mark S. Wallace Key Points Numerous analgesic agents can be used in the treatment of pain related to rheumatic disease. The…
Antinuclear Antibodies
55 Antinuclear Antibodies Stanford L. Peng, Joseph E. Craft Key Points The presence of antinuclear antibodies (ANAs) is characteristic of systemic lupus erythematosus (SLE), systemic sclerosis, inflammatory myositis, and Sjögren’s…
Muscle: Anatomy, Physiology, and Biochemistry
5 Muscle Anatomy, Physiology, and Biochemistry Mark S. Miller, Bradley M. Palme, Michael J. Toth, David M. Warshaw Key Points The structure and function of skeletal muscle and its neural…
Low Back Pain
47 Low Back Pain Rajiv Dixit Key Points Up to 80% of the population will experience low back pain (LBP), and degenerative changes of the lumbar spine is the most…
Treatment of Juvenile Idiopathic Arthritis
107 Treatment of Juvenile Idiopathic Arthritis Joyce J. Hsu, Tzielan Chang Lee, Christy I. Sandborg Key Points Juvenile idiopathic arthritis (JIA) is the umbrella term for the family of childhood…
Immune Complex–Mediated Small Vessel Vasculitis
91 Immune Complex–Mediated Small Vessel Vasculitis John H. Stone Key Points Vasculitis mediated by immune complexes (ICs) includes a heterogeneous group of disorders linked by inefficient or dysregulated clearance of…
Prostanoid Biology and Its Therapeutic Targeting
59 Prostanoid Biology and Its Therapeutic Targeting Leslie J. Crofford Key Points Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective anti-inflammatory, antipyretic, and analgesic compounds. There is little difference in the efficacy…
Clinical Features of Systemic Lupus Erythematosus
80 Clinical Features of Systemic Lupus Erythematosus Maria Dall’Era, David Wofsy Key Points Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by a relapsing-remitting course and a highly…
Relapsing Polychondritis
104 Relapsing Polychondritis Gaye Cunnane Key Points Relapsing polychondritis is a rare disorder that classically affects the cartilaginous structures of the ears and nose, resulting in “cauliflower ear” and “saddle…
