Fibromyalgia
52 Fibromyalgia Frederick Wolfe, Johannes J. Rasker Key Points Many issues that surround fibromyalgia are not scientific ones—it is widely agreed that pain and suffering are real; instead, the primary…
Etiology and Pathogenesis of Systemic Lupus Erythematosus
79 Etiology and Pathogenesis of Systemic Lupus Erythematosus Mary K. Crow Key Points Systemic lupus erythematosus (SLE) results from chronic and recurrent activation of the immune system, with production of…
Autoantibodies in Rheumatoid Arthritis
56 Autoantibodies in Rheumatoid Arthritis Felipe Andrade, Erika Darrah, Antony Rosen Key Points Autoantibodies in rheumatoid arthritis (RA) are important tools for diagnosis and for defining important pathogenic pathways in…
Fibroblasts and Fibroblast-like Synoviocytes
15 Fibroblasts and Fibroblast-like Synoviocytes Andrew Filer, Christopher D. Buckley Key Points Fibroblasts are programmed epigenetically to determine the unique structure and function of different organs and tissues. However, these…
Classification and Epidemiology of Systemic Vasculitis
87 Classification and Epidemiology of Systemic Vasculitis John H. Stone Key Points Vasculitis is a heterogeneous group of disorders linked by the primary finding of inflammation within blood vessel walls….
Principles of Epidemiology in Rheumatic Disease
30 Principles of Epidemiology in Rheumatic Disease Yvonne M. Golightly, Joanne M. Jordan Key Points Epidemiology is the study of the distribution of disease and its determinants in populations. Epidemiologic…
Endocrine Diseases and the Musculoskeletal System
121 Endocrine Diseases and the Musculoskeletal System Maurizio Cutolo Key Points Both hypothyroidism and hyperthyroidism are characterized by frequent symptomatic involvement of the musculoskeletal system. Diseases of the parathyroid gland…
Foot and Ankle Pain
49 Foot and Ankle Pain Mark D. Price, Christopher P. Chiodo Key Points The differential diagnosis for foot and ankle pain is vast. Localizing symptoms by anatomic region helps narrow…
Pregnancy in the Rheumatic Diseases
39 Pregnancy in the Rheumatic Diseases Eliza F. Chakravarty, Megan E. Clowse Key Points The majority of women with autoimmune diseases will have healthy and uneventful pregnancies, and the risk-benefit…
Experimental Models for Rheumatoid Arthritis
28 Experimental Models for Rheumatoid Arthritis Rikard Holmdahl Key Points Animal models are tools to mimic various aspects of rheumatoid arthritis (RA). There are many different animal models for RA,…
