Role of Complement in Systemic Lupus Erythematosus Pathogenesis
Chapter 20 Role of Complement in Systemic Lupus Erythematosus Pathogenesis Chau-Ching Liu, MD, PhD , Jeannine S. Navratil, MS , Amy H. Kao, MD, MPH , Susan Manzi, MD, MPH…
Biology of Dendritic Cells
Chapter 13 Biology of Dendritic Cells Virginia Pascual, MD , A. Karolina Palucka, MD , Jacques Banchereau, MD INTRODUCTION The primary role of the immune system is to protect the…
Antibodies to DNA
Chapter 22A Antibodies to DNA David S. Pisetsky, MD, PhD INTRODUCTION Antibodies to DNA (anti-DNA) are prototypic autoantibodies that are the serologic hallmark of systemic lupus erythematosus (SLE). These antibodies…
Quality of Life and Economic Aspects
Chapter 4 Quality of Life and Economic Aspects Ann E. Clarke, MD, MSc , Pantelis Panopalis, MD INTRODUCTION Systemic lupus erythematosus (SLE) primarily affects young women in the prime of…
Hormonal Influences in the Expression of Systemic Lupus Erythematosus
Chapter 9 Hormonal Influences in the Expression of Systemic Lupus Erythematosus Virginia Rider, PhD , Xiaolan Li, MD , Nabih I. Abdou, MD INTRODUCTION The ability of the immune system…
Overview of the Pathogenesis of Systemic Lupus Erythematosus
Chapter 6 Overview of the Pathogenesis of Systemic Lupus Erythematosus Sandeep Krishnan, MD, PhD , Bhabadeb Chowdhury, PhD , Yuang-Taung Juang, MD, PhD , George C. Tsokos, MD INTRODUCTION Systemic…
Antibodies and their Antigenic Targets in the Antiphospholipid Syndrome
Chapter 22B Antibodies and their Antigenic Targets in the Antiphospholipid Syndrome Bill Giannakopoulos, MB, BS, FRACP , Xiaokai Yan, PhD , Steven A. Krilis, MB, BS, PhD INTRODUCTION The antiphospholipid…
The Environment in the Pathogenesis of Systemic Lupus Erythematosus
Chapter 7 The Environment in the Pathogenesis of Systemic Lupus Erythematosus Amr H. Sawalha, MD , Bruce C. Richardson, MD, PhD INTRODUCTION Human lupus is a chronic relapsing autoimmune disease…
B-cells in Human Systemic Lupus Erythematosus
Chapter 11 B-cells in Human Systemic Lupus Erythematosus Stamatis-Nick C. Liossis, MD , George C. Tsokos, MD Among the numerous immunologic abnormalities encountered in patients with SLE, the most striking…
