RHEUMATOLOGY
Manifestations of Alkaptonuria and Ochronosis in Visceral Organs
Fig. 18.1 Heart and thoracic aorta. Focal pigmentation on the mitral and aortic valve and sporadically in the subendocardial layer of the myocardium. Ulcerative arteriosclerosis and numerous pigmented foci, especially…
Case Reports
Fig. 27.1 Ochronotic involvement of the tendon at the place of its insertion to the bone In this case report, we present the occurrence of peripheral enthesopathies in a patient…
Symptoms of Alkaptonuria and Ochronosis in the Ear
Fig. 17.1 (a) Section of the oval window: unstained histological section, pigmented bone cells on stapes base. (b) Promontorium section: unstained histological section, pigmented cells in periostal layer and on…
Clinical and Ultrasound Evaluation of Enthesopathy in Alkaptonuria in Romani (Gypsy) Community
Patient no. Age Gender Side Heel pain Thickening Gap in the tendon 1 30 F RT + + − LT + + − 2 37 F RT + ++ −…
Clinical Manifestation of Ochronotic Arthropathy in Spine
Fig. 11.1 Flattening of physiologic curves of the spine (thoracic kyphosis and lumbar lordosis). Initial stages of ochronotic changes in spine In addition to flattening of physiologic curves in ochronotic…
Analysis of X-Ray Symptomatology of Ochronotic Arthropathy in the Area of Peripheral Joints
Fig. 15.1 Knees: varus position in both knees, subchondral sclerotisation and asymmetrical narrowing of tibiofemoral articular slit. Changes are accentuated in the lateral part of articular slit of the left…
Clinical Manifestation of Ochronotic Arthropathy in Peripheral Joints
Fig. 13.1 Ochronosis. Open knee joint. Deposits of ochronotic pigment give the cartilage the blue-black colour Fig. 13.2 Distal epiphyseal end of femur. Map-like erosions of articular cartilage that has…
Analysis of X-Ray Symptomatology of Ochronotic Arthropathy in Spine
Fig. 12.1 Cervical spine: head in forward projection. Narrowing of intervertebral spaces with considerable subchondral sclerotisation of articular surfaces and non-homogeneous mild opacity of intervertebral spaces, uncovertebral arthrosis and arthrosis…
History of Nitisinone (NTBC)
Fig. 26.1 Callistemon spp. (Australian bottle-brush plant) Animal toxicity studies were carried out at ICI and subsequently Zeneca, which was established in 1993 by demerging of various business units of…