in Setting Up a Study and Data Collection

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on in Setting Up a Study and Data Collection

Fig. 1 Algorithm for setting up a rheumatology research project Create a Multidisciplinary Study Team (i.e., Clinicians, Epidemiologists, Biostatisticians, Ethicists, Patient Representatives, and Others, as Needed) Any rheumatology research is…

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Measurement of Severity of Injury After Articular Fracture and Correlation with Post-Traumatic Arthritis Development

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Measurement of Severity of Injury After Articular Fracture and Correlation with Post-Traumatic Arthritis Development

Fig. 24.1 These radiographs illustrate the tibial plafond fracture severity spectrum. Simple intra-articular fractures result from low energy impacts (left). As energy increases (moving from left to right in the…

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Potential Mechanisms of PTA: Oxidative Stress

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Potential Mechanisms of PTA: Oxidative Stress

Fig. 17.1 Blunt impact suppresses cartilage ATP production. Explant cartilage was harvested for ATP assay 24 or 48 h postimpact (7 J/cm2). Cartilage was harvested from control (non-impacted) explants and…

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Instability: Dynamic Loading Models

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Instability: Dynamic Loading Models

Fig. 9.1 Dynamic human cadaveric ankle loading model in which ankles were made incongruous with a coronally directed osteotomy of the anterior distal tibial surface displaced proximally 2.0 mm (a)….

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Biomarkers of PTA

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Biomarkers of PTA

Fig. 25.1 Framework for PTOA Pathomechanics. Modified from: Andriacchi and Mundermann 2006 [13] Pre-injury biomarker generation. As illustrated in Fig. 25.1, biomarker generation may begin in the pre-injury phase among…

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Aging and Post-Traumatic Arthritis

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Aging and Post-Traumatic Arthritis

Fig. 14.1 Systemic aging changes that could contribute to the development of osteoarthritis, including post-traumatic OA. Reprinted with permission from HSS Journal 2012; 8:19 Relationship Between Age and the Development…

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