60 Glucocorticoid Therapy Johannes W.G. Jacobs, Johannes W.J. Bijlsma Key Points Mode of action of glucocorticoids is genomic (via glucocorticoid receptor) and, in high dosages, also nongenomic. Glucocorticoids differ considerably…
61 Traditional DMARDs Methotrexate, Leflunomide, Sulfasalazine, Hydroxychloroquine, and Combination Therapies Amy C. Cannella, James R. O’dell Key Points Methotrexate is one of the most durable and frequently used disease-modifying antirheumatic…
50 Hand and Wrist Pain Carrie R. Swigart Key Points Patients with carpal tunnel syndrome typically present with nocturnal paresthesias associated with intermittent pain or paresthesia during the day. Ganglia…
51 Temporomandibular Joint Pain Daniel M. Laskin Key Points Temporomandibular joint (TMJ) pain must be distinguished from the pain that more commonly arises from the muscles of mastication (myofascial pain),…
109 Bacterial Arthritis Paul P. Cook, Dawd S. Siraj Key Points Acute bacterial arthritis is a medical emergency that warrants rapid, accurate diagnosis and immediate treatment along with appropriate consultation…
44 The Eye and Rheumatic Diseases James T. Rosenbaum Key Points Symptoms of uveitis vary widely based on the location of the inflammation within the eye and the suddenness of…
40 History and Physical Examination of the Musculoskeletal System John M. Davis, III., Kevin G. Moder, Gene G. Hunder Key Points Taking a detailed and accurate history is crucial for…
115 Poststreptococcal Arthritis and Rheumatic Fever Allan Gibofsky, John B. Zabriskie Key Points Acute rheumatic fever (ARF) is a delayed, nonsuppurative sequel of a pharyngeal infection with group A streptococci….
66 Analgesic Agents in Rheumatic Disease Gregory R. Polston, Mark S. Wallace Key Points Numerous analgesic agents can be used in the treatment of pain related to rheumatic disease. The…
55 Antinuclear Antibodies Stanford L. Peng, Joseph E. Craft Key Points The presence of antinuclear antibodies (ANAs) is characteristic of systemic lupus erythematosus (SLE), systemic sclerosis, inflammatory myositis, and Sjögren’s…
