Chapter 21 Immune Complexes in Systemic Lupus Erythematosus Mark H. Wener, MD INTRODUCTION Antigen-antibody complexes mediate much of the inflammation and tissue dysfunction associated with SLE. Deposition of ICs within…
Chapter 16 Autoantibodies in Systemic Lupus Erythematosus David Isenberg, MD , Matthew Adler, MRCP INTRODUCTION Overview of Autoantibodies in SLE One of the hallmarks of systemic lupus erythematosus (SLE) is…
Chapter 20 Role of Complement in Systemic Lupus Erythematosus Pathogenesis Chau-Ching Liu, MD, PhD , Jeannine S. Navratil, MS , Amy H. Kao, MD, MPH , Susan Manzi, MD, MPH…
Chapter 19 Complement Deficiencies in Human Systemic Lupus Erythematosus (SLE) and SLE Nephritis: Epidemiology and Pathogenesis C. Yung Yu, Dphil , Georges Hauptmann, MD, PhD , Yan Yang, MD, PhD…
Chapter 13 Biology of Dendritic Cells Virginia Pascual, MD , A. Karolina Palucka, MD , Jacques Banchereau, MD INTRODUCTION The primary role of the immune system is to protect the…
Chapter 22A Antibodies to DNA David S. Pisetsky, MD, PhD INTRODUCTION Antibodies to DNA (anti-DNA) are prototypic autoantibodies that are the serologic hallmark of systemic lupus erythematosus (SLE). These antibodies…
Chapter 4 Quality of Life and Economic Aspects Ann E. Clarke, MD, MSc , Pantelis Panopalis, MD INTRODUCTION Systemic lupus erythematosus (SLE) primarily affects young women in the prime of…
Chapter 9 Hormonal Influences in the Expression of Systemic Lupus Erythematosus Virginia Rider, PhD , Xiaolan Li, MD , Nabih I. Abdou, MD INTRODUCTION The ability of the immune system…
Chapter 6 Overview of the Pathogenesis of Systemic Lupus Erythematosus Sandeep Krishnan, MD, PhD , Bhabadeb Chowdhury, PhD , Yuang-Taung Juang, MD, PhD , George C. Tsokos, MD INTRODUCTION Systemic…
