Fig. 16.1 Schematic representation of the innervation of normal (top) and degenerated (bottom) intervertebral discs (IVDs), as well as the origin of sensory nerve fibers that innervate them. In the…
Fig. 21.1 Schematic representation of gene targeting in mice. Embryonic stem cells (ES) are collected from mouse blastocysts (1). ES are cultivated in vitro (2) and a targeting vector is…
Fig. 3.1 Development of the notochord and nucleus pulposus. (a) The nucleus is derived from the notochord, a rod-shaped embryonic structure that lies under the neural tube. Sclerotome condenses around…
Fig. 8.1 Distinct domain structures and differential cell localization of ADAMTS and ADAM proteinases. The domain structures of ADAMTS5 and of a typical ADAM proteinase are shown in the context…
Fig. 6.1 The axial skeleton is hypoxic and expresses HIF-1α. (a) Characterization of hypoxia- inducible reporter mice (5XHRE-LacZ reporter). Note activation of the reporter construct in mesenchymal condensations by β-gal…
Fig. 1.1 (a–c) Judet’s orthopedic table allowing a stable position of the pelvis and of the operated lower limb in the desired position The sacrum rests on a scooped out…
Fig. 3.1 Route of the Hueter approach In this chapter, we present the surgical technique and our results and discuss the advantages and disadvantages of the concept. Surgical Technique General…
Fig. 13.1 The short-stemmed Metha prosthesis is coated on the proximal, metaphyseal area, which supports bony ingrowth and secondary stability. The tip is smooth and is only needed for primary…
Fig. 12.1 Attachment of the reference arrays Fig. 12.2 Acquisition of the medial condyle point Then the head-neck junction point is landmarked as well; this point is going to be…
Fig. 5.1 The Smith-Petersen or Hueter approach uses the interval between the TFL (4) and the sartorius (1). The TFL (4) and the abductors, gluteus minimus (5), and gluteus medius…
