T-Cells and Systemic Lupus Erythematosus
Chapter 10 T-Cells and Systemic Lupus Erythematosus Robert Hoffman, DO , Marcos E. Maldonado, MD INTRODUCTION AND BACKGROUND The pathogenesis of systemic lupus erythematosus (SLE) is complex and appears to…
Epidemiology of Systemic Lupus Erythematosus
Chapter 1 Epidemiology of Systemic Lupus Erythematosus Ana M. Bertoli, MD , Graciela S. Alarcón, MD, MPH INTRODUCTION Systemic lupus erythematosus (SLE) is one of the most common autoimmune diseases.1…
What Do Mouse Models Teach Us about Human Systemic Lupus Erythematosus?
Chapter 17 What Do Mouse Models Teach Us about Human Systemic Lupus Erythematosus? Kui Liu, PhD , Chandra Mohan, MD, PhD INTRODUCTION Systemic lupus erythematosus (SLE) is an autoimmune disease…
Infection and Autoimmunity
Chapter 15 Infection and Autoimmunity Brian D. Poole, PhD , Judith A. James, MD, PhD Infections are associated with both the etiology and morbidity of systemic lupus erythematosus (SLE). Mounting…
The Genetics of Lupus
Chapter 8 The Genetics of Lupus Bahram Namjou, MD , Jennifer A. Kelly, MPH , John B. Harley, MD, PhD INTRODUCTION Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune…
Genes and Genetics of Murine Lupus
Chapter 18 Genes and Genetics of Murine Lupus Shozo Izui, MD INTRODUCTION Systemic lupus erythematosus (SLE) is a disorder of systemic autoimmunity characterized by the formation of a variety of…
Immune Complexes in Systemic Lupus Erythematosus
Chapter 21 Immune Complexes in Systemic Lupus Erythematosus Mark H. Wener, MD INTRODUCTION Antigen-antibody complexes mediate much of the inflammation and tissue dysfunction associated with SLE. Deposition of ICs within…
Autoantibodies in Systemic Lupus Erythematosus
Chapter 16 Autoantibodies in Systemic Lupus Erythematosus David Isenberg, MD , Matthew Adler, MRCP INTRODUCTION Overview of Autoantibodies in SLE One of the hallmarks of systemic lupus erythematosus (SLE) is…
