Large Animal Models of Disc Degeneration

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Large Animal Models of Disc Degeneration

18.3 Types of Models Used in Intervertebral Disc Research Intervertebral disc research involving various regions of the spine has been useful in assessing the physical, histological, and biomechanical characteristics of…

read more

Tissue Engineering of the Intervertebral Disc

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Tissue Engineering of the Intervertebral Disc

, Paul Santerre2, Eric Massicotte3, 4 and Mark Hurtig5 (1) Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada (2) Institute of Biomaterials and Biomedical Engineering, University…

read more

Genetic Basis of Intervertebral Disc Degeneration

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Genetic Basis of Intervertebral Disc Degeneration

Fig. 10.1 Concepts of Mendelian inheritance. (a) In dominant ­inheritance, one parent carries the disease-causing allele D, with one copy sufficient to show the phenotype. Offspring who inherited the D…

read more

The Nonsurgical Treatment of Back Pain

Mar 25, 2017 by in ORTHOPEDIC Comments Off on The Nonsurgical Treatment of Back Pain

Treatment Therapy Stage of symptoms Nonsurgical therapies Patient education Acute Activity modification Acute Behavioral therapy Acute and chronic Exercise therapy Subacute and chronic Oral medication Non-narcotic analgesic Acute Narcotic analgesic…

read more

Gene Therapy Approaches for Disc Regeneration

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Gene Therapy Approaches for Disc Regeneration

Survival of luciferase-expressing stem cells following implantation into the intervertebral disc region. Stem cells expressing the luciferase gene were implanted in a caudal disc space in the rat. At each…

read more
Get Clinical Tree app for offline access