Clinical Features and Pathobiology of Chordoma

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Clinical Features and Pathobiology of Chordoma

Fig. 17.1 Typical MRI appearance of large sacral chordoma 17.3 Clinical Features Patients diagnosed with a chordoma most commonly present with pain, regardless of location (Bergh et al. 2000; Boriani…

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Proteoglycans of the Intervertebral Disc

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Proteoglycans of the Intervertebral Disc

Fig. 4.1 Immunolocalization of aggrecan (a), versican (b), and toluidine blue-stained proteoglycan (c) in a 14-week gestational age fetal human intervertebral disc and adjacent cartilaginous vertebral body rudiment cartilages. Higher-power…

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Surgical Indications for Lumbar Degenerative Disease

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Surgical Indications for Lumbar Degenerative Disease

Fig. 13.1 Sagittal T2-weighted lumbar MRI image demonstrating degeneration of the L4–5 intervertebral disc (white arrow). Water has high signal intensity on T2-weighted MRI imaging. As the disc degenerates, it…

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Imaging Modalities for Studying Disc Pathology

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Imaging Modalities for Studying Disc Pathology

Fig. 12.1 Representative proton T2 MRI (grayscale) and corresponding T1ρ maps (in color overlaid on grayscale T1ρ-weighted image) of the lumbar discs from a 52-year-old female (a) and a 35-year-old…

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Epidemiology of Lumbar Disc Degeneration

Mar 25, 2017 by in ORTHOPEDIC Comments Off on Epidemiology of Lumbar Disc Degeneration

Author and year Sample size Race Age Gender Reduced signal intensity Reduced disc height Bulging Annular tears High-intensity zone Videman (1995)a 232 Finnish 49.3 (35–69) 100 % M L1/2 41.6…

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The Intervertebral Disc: Overview of Disc Mechanics

Mar 25, 2017 by in ORTHOPEDIC Comments Off on The Intervertebral Disc: Overview of Disc Mechanics

Fig. 2.1 Schematic representations of the adult intervertebral disc. (a) Midsagittal cross section showing anatomical regions. (b) Three-dimensional view illustrating AF lamellar structure (Adapted from Smith et al. 2011) The…

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