80 Clinical Features of Systemic Lupus Erythematosus Maria Dall’Era, David Wofsy Key Points Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by a relapsing-remitting course and a highly…
102 Proliferative Bone Diseases Reuven Mader Key Points Diffuse idiopathic skeletal hyperostosis (DISH) is usually defined by the presence of large flowing osteophytes connecting at least four vertebrae, typically in…
104 Relapsing Polychondritis Gaye Cunnane Key Points Relapsing polychondritis is a rare disorder that classically affects the cartilaginous structures of the ears and nose, resulting in “cauliflower ear” and “saddle…
111 Mycobacterial Infections of Bones and Joints Eric M. Ruderman, John P. Flaherty Key Points Global rates of tuberculosis disease have increased due to the expanding human immunodeficiency virus pandemic…
117 Sarcoidosis Nadera J. Sweiss, Robert P. Baughman Key Points Sarcoidosis is a heterogeneous multisystem inflammatory disease of unknown cause characterized by the development and accumulation of noncaseating granulomata in…
112 Fungal Infections of Bones and Joints Eric M. Ruderman, John P. Flaherty Key Points Fungi are an infrequent but clinically important cause of bone and joint infections. These infections…
108 Pediatric Systemic Lupus Erythematosus, Dermatomyositis, Scleroderma, and Vasculitis Ronald M. Laxer, Susanne M. Benseler Key Points Pediatric systemic lupus erythematosus (SLE) accounts for 11% of patients referred to pediatric…
73 Sjögren’s Syndrome E. William St. Clair Key Points Sjögren’s syndrome is divided into primary and secondary forms. The primary form occurs in approximately 0.1% to 0.6% of the general…
98 Pathogenesis of Osteoarthritis Paul E. Di Cesare, Dominik R. Haudenschild, Jonathan Samuels, Steven B. Abramson Key Points Osteoarthritis is a degenerative joint disease, occurring primarily in older individuals, characterized…
