History of Nitisinone (NTBC)

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on History of Nitisinone (NTBC)

Fig. 26.1 Callistemon spp. (Australian bottle-brush plant) Animal toxicity studies were carried out at ICI and subsequently Zeneca, which was established in 1993 by demerging of various business units of…

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Pathological Anatomy and Histology of Ochronosis

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on Pathological Anatomy and Histology of Ochronosis

Fig. 20.1 Ochronosis in joint tissues. Histological images of the connective tissue from the tendons and fibrous capsule of a patient with AKU showing deposition of ochronotic pigment (a–g). Photographs…

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Metabolism of Aromatic Amino Acids

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on Metabolism of Aromatic Amino Acids

Fig. 4.1 Conversion of phenylalanine to tyrosine 1. Fumarate and acetoacetate   2. Dopamine, adrenaline and noradrenaline   3. Melanins   4. Thyroid hormones – thyroxin and triiodothyronine   Degradation…

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Therapy of Alkaptonuria

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on Therapy of Alkaptonuria

© Springer International Publishing Switzerland 2015Jozef Rovenský, Tibor Urbánek, Boldišová Oľga and James A. Gallagher (eds.)Alkaptonuria and Ochronosis10.1007/978-3-319-15108-3_25 25. Therapy of Alkaptonuria Jozef Rovenský1, 2   and Tibor Urbánek1   (1) National Institute of Rheumatic Diseases, Piešťany, Slovakia (2) Institute of…

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Coincidence of Alkaptonuric Ochronosis with Other Diseases

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on Coincidence of Alkaptonuric Ochronosis with Other Diseases

© Springer International Publishing Switzerland 2015Jozef Rovenský, Tibor Urbánek, Boldišová Oľga and James A. Gallagher (eds.)Alkaptonuria and Ochronosis10.1007/978-3-319-15108-3_23 23. Coincidence of Alkaptonuric Ochronosis with Other Diseases Jozef Rovenský1, 2   and Oľga Lukáčová1   (1) National Institute of Rheumatic Diseases, Piešťany,…

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Differential Diagnosis of the Disease

Oct 14, 2016 by in RHEUMATOLOGY Comments Off on Differential Diagnosis of the Disease

© Springer International Publishing Switzerland 2015Jozef Rovenský, Tibor Urbánek, Boldišová Oľga and James A. Gallagher (eds.)Alkaptonuria and Ochronosis10.1007/978-3-319-15108-3_24 24. Differential Diagnosis of the Disease Jozef Rovenský1, 2   and Oľga Lukáčová1   (1) National Institute of Rheumatic Diseases, Piešťany, Slovakia (2)…

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