Genetics of Human SLE
Chapter 4 Genetics of Human SLE Yun Deng, Betty P. Tsao The complex etiopathology of systemic lupus erythematosus (SLE) has been attributed to “cross talk” between multiple genetic predispositions and…
The Structure and Derivation of Antibodies and Autoantibodies
Chapter 8 The Structure and Derivation of Antibodies and Autoantibodies Giovanni Franchin, Yong-Rui Zou, Betty Diamond The humoral immune response protects an organism from environmental pathogens by producing antibodies (immunoglobulins)…
Cytokines and Interferons in Lupus
Chapter 7 Cytokines and Interferons in Lupus Mary K. Crow, Timothy B. Niewold, Kyriakos A. Kirou The immunopathology of systemic lupus erythematosus (SLE) has traditionally been attributed to the deposition…
Neural-Immune Interactions: Principles and Relevance to SLE
Chapter 13 Neural-Immune Interactions Principles and Relevance to SLE Cherie L. Butts, Esther M. Sternberg The immune and central nervous systems are the body’s primary tools for interfacing with constant…
Regulatory Cells in SLE
Chapter 10 Regulatory Cells in SLE Antonio La Cava Several subsets of immune cells endowed with regulatory functions can significantly influence the onset and progression of SLE. As a disease…
The Innate Immune System in SLE
Chapter 6 The Innate Immune System in SLE Lukas Bossaller, Ann Marshak-Rothstein Adaptive immunity and innate immunity can be distinguished from each other by the nature of the receptors involved…
Definition and Classification of Lupus and Lupus-Related Disorders
Chapter 1 Definition and Classification of Lupus and Lupus-Related Disorders Jinoos Yazdany, Maria Dall’Era The goal of this chapter is to introduce the reader to the terminology and classification criteria…
