Chapter 12 Abnormalities in Immune Complex Clearance and Fcγ Receptor Function Jane E. Salmon, Robert P. Kimberly Systemic lupus erythematosus (SLE), the prototype human disease mediated by immune complexes, is…
Chapter 16 Mechanisms of Tissue Damage—Free Radicals and Fibrosis Biji T. Kurien, Chandra Mohan, R. Hal Scofield Systemic lupus erythematosus (SLE) is a chronic, complex inflammatory autoimmune disease involving multisystem…
Chapter 46 Clinical Measures, Metrics, and Indices Zahi Touma, Dafna D. Gladman, Murray B. Urowitz Systemic lupus erythematosus (SLE) is a protean, multisystem complex disease characterized by remissions and exacerbations….
Chapter 32 Management of Sjögren Syndrome in Patients with SLE Hendrika Bootsma, Hjalmar R. Bouma, Frans G.M. Kroese, Arjan Vissink, Daniel J. Wallace Sjögren syndrome (SS) is an autoimmune inflammatory…
Chapter 31 Ocular, Aural, and Oral Manifestations James T. Rosenbaum, Dennis R. Trune, Andre Barkhuizen, Lyndell Lim Systemic Lupus Erythematosus and the Eye Systemic lupus erythematosus (SLE) may affect any…
Chapter 2 The Epidemiology of Lupus S. Sam Lim, Cristina Drenkard Epidemiology is the study of the frequency and distribution of disease and the determinants associated with disease occurrence and…
Chapter 56 Investigational Agents and Future Therapy for SLE Georg H. Stummvoll, Josef S. Smolen When Moriz Kaposi1 in 1872 dealt with the therapy of systemic lupus erythematosus (SLE) for…
Chapter 22 Overview and Clinical Presentation Andrea Hinojosa-Azaola, Jorge Sánchez-Guerrero Systemic lupus erythematosus (SLE) is considered the most clinically and serologically diverse autoimmune disease because it can affect almost any…
Chapter 39 Drug-Induced Lupus Etiology, Pathogenesis, and Clinical Aspects Dipak Patel, Bruce Richardson Lupus flares when genetically predisposed people encounter drugs or environmental agents that trigger the disease. Although the…
Chapter 34 Hematologic and Lymphoid Abnormalities in SLE George A. Karpouzas Hematologic abnormalities are common in systemic lupus erythematosus (SLE) and are often presenting manifestations of the disease. Sometimes their…
