Chapter 51 Specialized Treatment Approaches and Niche Therapies for Lupus Subsets Daniel J. Wallace Treatment of Patients with Systemic Lupus Erythematosus and End-Stage Renal Disease Incidence and Prevalence Patients with…
Chapter 26 Pathogenesis and Treatment of Atherosclerosis in Lupus Maureen McMahon, Brian Skaggs, Jennifer Grossman Introduction Premature atherosclerosis is a major comorbid condition in systemic lupus erythematosus (SLE). Although typical…
Chapter 44 Differential Diagnosis and Disease Associations Meenakshi Jolly, Serene Francis, Winston Sequeira Systemic lupus erythematosus (SLE) exhibits a variety of signs and symptoms among patients, which frequently poses diagnostic…
Chapter 14 Complement and SLE Chau-Ching Liu, Susan Manzi, Joseph M. Ahearn Historical Overview The complement system is arguably linked more intimately to systemic lupus erythematosus (SLE) than to any…
Chapter 42 Clinical Aspects of the Antiphospholipid Syndrome Aisha Lateef, Michelle Petri Introduction The antiphospholipid syndrome (APS), an acquired thrombophilia, is characterized by vascular thrombosis and/or fetal loss in the…
Chapter 29 Clinical Aspects of the Nervous System Sterling G. West Neuropsychiatric manifestations of systemic lupus erythematosus (NP-SLE) are frequent, vary from mild to severe, and are often difficult to…
Chapter 4 Genetics of Human SLE Yun Deng, Betty P. Tsao The complex etiopathology of systemic lupus erythematosus (SLE) has been attributed to “cross talk” between multiple genetic predispositions and…
Chapter 8 The Structure and Derivation of Antibodies and Autoantibodies Giovanni Franchin, Yong-Rui Zou, Betty Diamond The humoral immune response protects an organism from environmental pathogens by producing antibodies (immunoglobulins)…
Chapter 7 Cytokines and Interferons in Lupus Mary K. Crow, Timothy B. Niewold, Kyriakos A. Kirou The immunopathology of systemic lupus erythematosus (SLE) has traditionally been attributed to the deposition…
Chapter 13 Neural-Immune Interactions Principles and Relevance to SLE Cherie L. Butts, Esther M. Sternberg The immune and central nervous systems are the body’s primary tools for interfacing with constant…
