Quality of Life and Economic Aspects
Chapter 4 Quality of Life and Economic Aspects Ann E. Clarke, MD, MSc , Pantelis Panopalis, MD INTRODUCTION Systemic lupus erythematosus (SLE) primarily affects young women in the prime of…
Hormonal Influences in the Expression of Systemic Lupus Erythematosus
Chapter 9 Hormonal Influences in the Expression of Systemic Lupus Erythematosus Virginia Rider, PhD , Xiaolan Li, MD , Nabih I. Abdou, MD INTRODUCTION The ability of the immune system…
Overview of the Pathogenesis of Systemic Lupus Erythematosus
Chapter 6 Overview of the Pathogenesis of Systemic Lupus Erythematosus Sandeep Krishnan, MD, PhD , Bhabadeb Chowdhury, PhD , Yuang-Taung Juang, MD, PhD , George C. Tsokos, MD INTRODUCTION Systemic…
Antibodies and their Antigenic Targets in the Antiphospholipid Syndrome
Chapter 22B Antibodies and their Antigenic Targets in the Antiphospholipid Syndrome Bill Giannakopoulos, MB, BS, FRACP , Xiaokai Yan, PhD , Steven A. Krilis, MB, BS, PhD INTRODUCTION The antiphospholipid…
The Environment in the Pathogenesis of Systemic Lupus Erythematosus
Chapter 7 The Environment in the Pathogenesis of Systemic Lupus Erythematosus Amr H. Sawalha, MD , Bruce C. Richardson, MD, PhD INTRODUCTION Human lupus is a chronic relapsing autoimmune disease…
B-cells in Human Systemic Lupus Erythematosus
Chapter 11 B-cells in Human Systemic Lupus Erythematosus Stamatis-Nick C. Liossis, MD , George C. Tsokos, MD Among the numerous immunologic abnormalities encountered in patients with SLE, the most striking…
Disease Development and Outcome
Chapter 3 Disease Development and Outcome Rosalind Ramsey-Goldman, MD, DrPH , Dafna Gladman, MD NATURAL HISTORY Systemic lupus erythematosus (SLE) has been recognized as a disease of exacerbations and remission…
Cytokines in Systemic Lupus Erythematosus
Chapter 12 Cytokines in Systemic Lupus Erythematosus Violeta Rus, MD , Charles S. Via, MD INTRODUCTION Systemic lupus erythematosus is characterized by a loss of tolerance to nuclear antigens and…
Biomarkers of Disease Activity
Chapter 5 Biomarkers of Disease Activity Larissa Lapteva, MD , Gabor G. Illei, MD INTRODUCTION Systemic lupus erythematosus has a characteristically waxing and waning course that can range in severity…
