Integrative Genomics
When viewed from a clinical perspective, few of the common pediatric rheumatic diseases appear to be genetically determined. Family histories are rarely positive for diseases such as juvenile idiopathic arthritis…
Adaptive Immunity and Autoimmunity: Translation from Bench to Bedside
The Adaptive Immune Response Most childhood autoimmune diseases are complex, multifactorial diseases. Through interactions with a defined genetic susceptibility, other, mostly unknown, environmental factors play a role in the pathogenesis….
Pediatric Rheumatology: The Study of Rheumatic Diseases in Childhood and Adolescence
What are Rheumatic Diseases? Rheumatic diseases are a diverse group of chronic diseases united by the presence of chronic inflammation, usually of unknown cause, affecting structures of the musculoskeletal system,…
Tibial Plateau Fractures
Additional videos related to the subject of this chapter are available from the Medizinische Hochschule Hannover collection. The following videos are included with this chapter and may be viewed at…
Intracapsular Hip Fractures
Additional videos related to the subject of this chapter are available from the Medizinische Hochschule Hannover collection. The following videos are included with this chapter and may be viewed at…
Closed Fracture Management
Introduction James P. Waddell Introduction Nonoperative management of fractures is presumably as old as humankind. One would therefore anticipate that as part of the evolutionary biology of humans that there would…
Principles of Internal Fixation
Additional videos related to the subject of this chapter are available from the Medizinische Hochschule Hannover collection. The following videos are included with this chapter and may be viewed at…
Compartment Syndromes
Additional videos related to the subject of this chapter are available from the Medizinische Hochschule Hannover collection. The following videos are included with this chapter and may be viewed at…
Amputations in Trauma
General Principles History Amputation is no longer only the result of traumatic amputation or the real or perceived failure of limb salvage. Rather, amputation is now considered a viable and…
Pathologic Fractures
Introduction Pathologic fractures can be a source of diagnostic and therapeutic challenge to the practicing orthopaedic surgeon. These often unexpected fractures can be a significant cause of anxiety for patients,…
