RHEUMATOLOGY

Cartilage

Dec 21, 2016 by in RHEUMATOLOGY Comments Off on Cartilage

Cartilage Avneesh Chhabra, Gaurav K. Thawait, and Theodoros Soldatos The articular surfaces of synovial joints are covered by hyaline cartilage, which protects the underlying subchondral bones by distributing loads and…

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Reviews and Meta-analyses in Rheumatology

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Reviews and Meta-analyses in Rheumatology

Parameters that are commonly extracted from studies Characteristics of the manuscript Author Publication year Study duration Study design Factors related to risk of bias Participant characteristics Number Age Sex Diagnosis/criteria…

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Genetic Association, and Genomic Studies

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Genetic Association, and Genomic Studies

Fig. 1 Types of biomarkers that can be used at different stages of rheumatoid arthritis The majority of biomarkers in RA are also molecular like autoantibodies, cytokines, and acute-phase reactants….

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Directions

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Directions

, Yusuf Yazici2 and Emmanuel Lesaffre3, 4 (1) Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey (2) Division of Rheumatology, NYU Hospital for Joint Diseases, New…

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Issues in Study Design and Reporting

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Issues in Study Design and Reporting

, Emmanuel Lesaffre2, 3 and Yusuf Yazici4 (1) Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey (2) Department of Biostatistics, Erasmus MC, Rotterdam, The Netherlands (3)…

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Issues Relevant to Observational Studies, Registries, and Administrative Health Databases in Rheumatology

Nov 27, 2016 by in RHEUMATOLOGY Comments Off on Issues Relevant to Observational Studies, Registries, and Administrative Health Databases in Rheumatology

  RCTs Observational studies Strengths Randomization Large sample sizes and greater statistical power Blinding Greater external validity (more representative population) Limitations External validity is limited (usually highly selected population) Case…

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