Total Ankle Arthroplasty in the Varus Ankle
Total Ankle Arthroplasty in the Varus Ankle James K. DeOrio INTRODUCTION The most common deformity presentation with arthritis in the ankle is the varus ankle. Given the large number of…
MUSCULOSKELETAL MEDICINE
Salto-Talaris Total Ankle Arthroplasty: Features, Surgical Technique, and Results
Salto-Talaris Total Ankle Arthroplasty: Features, Surgical Technique, and Results James P. Halloran Selene G. Parekh SALTO-TALARIS TOTAL ANKLE ARTHROPLASTY Total ankle arthroplasty (TAA) has become a topic of increasing interest…
INBONE Implant: Features, Technique, and Results
INBONE Implant: Features, Technique, and Results John G. Anderson Donald R. Bohay C. Luke Rust Nicholas A. Cheney FEATURES The INBONE (Wright Medical, Arlington, TN) Total Ankle system, released for…
Global Systems Available
Global Systems Available Warren Latham Pradeep Alexander Johnny Lau OVERVIEW Total ankle arthroplasty (TAA) has two main design concepts: fixed/constrained and mobile bearing. Initial devices were highly constrained, whereas second-…
Patient Selection, Surgical Indications, and Preoperative Planning
Patient Selection, Surgical Indications, and Preoperative Planning Keith L. Wapner Anthony R. Ndu Total ankle replacement (TAR) has become a successful alternative to fusion for end-stage arthritis of the tibiotalar…
Walking Mechanics Following Surgical Interventions for Ankle Arthritis
Walking Mechanics Following Surgical Interventions for Ankle Arthritis Robin M. Queen Robert J. Butler THE BIOMECHANICS OF NORMAL WALKING Walking gait consists of two phases known as the support phase…
Patient Registries for International Harmonized Clinical Development
Fig. 11.1 Number of registrants in Remudy national dystrophinopathy registry. As of May 2014, 1,293 patients were registered in this national registry from all over Japan. Blue bars show monthly…
Translational Research on DMD in Japan
Chemical Chemical characteristics Advantages Disadvantages Negatively charged Good solubility – long half-life Nuclease and RNase H resistant Do not enter the heart Toxicity Uncharged Relatively safe Nuclease and RNase H…
Myotonic Dystrophy
Fig. 3.1 Multisystemic symptoms of DM 3.2 Clinical Features 3.2.1 Adult-Onset DM1 3.2.1.1 Muscle Weakness The predominant symptom of adult-onset DM1 is facial and distal muscle weakness. Facial weakness is…
Muscular Dystrophy Clinical Trial Network in Japan
Fig. 12.1 Main purposes and resources of the MDCTN As of April 2015, 33 clinical institutes distributed over all four main islands of Japan have joined the MDCTN (Fig. 12.2); these…
