Fig. 8.1 Left: illustrates displacement of a lateral tibial plateau fracture model used to assess the effect of displacement on observed contact stresses. Right: shows that greater joint displacement leads…
Fig. 17.1 Blunt impact suppresses cartilage ATP production. Explant cartilage was harvested for ATP assay 24 or 48 h postimpact (7 J/cm2). Cartilage was harvested from control (non-impacted) explants and…
Fig. 9.1 Dynamic human cadaveric ankle loading model in which ankles were made incongruous with a coronally directed osteotomy of the anterior distal tibial surface displaced proximally 2.0 mm (a)….
Fig. 25.1 Framework for PTOA Pathomechanics. Modified from: Andriacchi and Mundermann 2006 [13] Pre-injury biomarker generation. As illustrated in Fig. 25.1, biomarker generation may begin in the pre-injury phase among…
Fig. 14.1 Systemic aging changes that could contribute to the development of osteoarthritis, including post-traumatic OA. Reprinted with permission from HSS Journal 2012; 8:19 Relationship Between Age and the Development…
Fig. 12.1 Histologic cross section of a normal knee joint (Courtesy of Edward DiCarlo, MD, Hospital for Special Surgery, New York, NY) Under physiological conditions, the subchondral bone adapts its…
First author Year Mouse strain Phenotype Outcome Reference Fitzgerald 2008 MRL/MpJ Knee articular cartilage defects, ear wounds Able to heal full-thickness knee articular cartilage defects, able to heal 2-mm ear…
Fig. 23.1 PTA after previous both column plating of an acetabular fracture Bone Stock Patients with PTA from acetabular fractures treated nonoperatively may have altered bony anatomy secondary to remodeling…
Fig. 11.1 Toluidine blue staining of a cartilage biopsy specimen overlying a bone bruise harvested from an ACL-injured patient before ACL reconstruction (from [6]). This specimen was histologically graded as…
Fig. 7.1 Left: Setup to initiate ACL rupture injuries, consisting of custom platens designed to hold the knee and ankle joints, a load cell, and a tube for administering anesthesia,…
