Musculoskeletal Key

Short Circuit

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Short Circuit

Toll-like receptors (TLRs) play a significant role in the development and maintenance of neuropathic pain and are expressed widely within the central nervous system on neurons, microglia, and astrocytes. TLRs…

read more

The Cutting Edge

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on The Cutting Edge

When caring for spine patients, accurate diagnosis is essential, as interventional treatments are only effective when the true pain generator is correctly identified. Diagnostic procedures generally fall into provocative tests,…

read more

Dual Frontiers Cancer and Palliative Care

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Dual Frontiers Cancer and Palliative Care

The World Health Organization’s definition of palliative care emphasizes its role as a quality-of-life-enhancing intervention for patients and families experiencing life-threatening illnesses, recommending its early implementation alongside curative therapies. This…

read more

The First Strike

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on The First Strike

The principles of acute pain management are grounded in an understanding of the biopsychosocial factors that shape the pain experience. In individuals with acute pain, the interaction of biological, psychological,…

read more

Healing from Within

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Healing from Within

This article reviews 6 categories of regenerative therapies for chronic pain, including cell-based therapies, biologics, gene therapy, exosomes, tissue engineering, and biophysical stimuli. While mesenchymal stem cells, bone marrow aspirate…

read more

Rewiring Pain

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Rewiring Pain

Neuromodulation is an expanding field within pain medicine that modifies nervous system activity by applying electrical stimulation. Devices may be applied internally or externally, ranging from non-invasive devices applied to…

read more

Breaking the Cycle

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Breaking the Cycle

This article provides a comprehensive, multidisciplinary approach to chronic pain management that integrates pharmacologic treatments, physical therapy, psychological interventions, and complementary therapies. It emphasizes individualized care, highlighting both traditional and…

read more

Prescriptions with Precision

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Prescriptions with Precision

The use of pain medications with distinct mechanisms of action exemplifies precise prescribing aimed at enhancing pain relief, reducing side effects, and improving the patient experience in both acute and…

read more

Beyond Pills

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Beyond Pills

Chronic pain affects over 50 million Americans and contributes to rising disability, opioid dependence, and healthcare utilization. As the limitations of pharmacologic-only strategies become increasingly evident, integrative approaches offer a…

read more

Motion as Medicine

Jul 12, 2026 by drzezo in PHYSICAL MEDICINE & REHABILITATION Comments Off on Motion as Medicine

Movement-based therapies use physical activity to alleviate pain, improve function, and enhance overall well-being. Evidence shows that regular movement can reduce inflammation, modulate pain pathways, and reduce the incidence of…

read more