Integrative Genomics
When viewed from a clinical perspective, few of the common pediatric rheumatic diseases appear to be genetically determined. Family histories are rarely positive for diseases such as juvenile idiopathic arthritis…
Adaptive Immunity and Autoimmunity: Translation from Bench to Bedside
The Adaptive Immune Response Most childhood autoimmune diseases are complex, multifactorial diseases. Through interactions with a defined genetic susceptibility, other, mostly unknown, environmental factors play a role in the pathogenesis….
Pediatric Rheumatology: The Study of Rheumatic Diseases in Childhood and Adolescence
What are Rheumatic Diseases? Rheumatic diseases are a diverse group of chronic diseases united by the presence of chronic inflammation, usually of unknown cause, affecting structures of the musculoskeletal system,…
