RHEUMATOLOGY

Immune Tolerance Defects in Lupus

Sep 1, 2016 by in RHEUMATOLOGY Comments Off on Immune Tolerance Defects in Lupus

Chapter 19 Immune Tolerance Defects in Lupus Ram Raj Singh, Shweta Dubey, Julia Pinkhasov The presence of autoantibodies against a variety of ubiquitous self-antigens is a hallmark of systemic lupus…

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SLE and Infections

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Chapter 45 SLE and Infections Judith A. James, Andrea L. Sestak, Evan S. Vista Infections in systemic lupus erythematosus (SLE) remain a significant source of morbidity and mortality. Both the…

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Epigenetics of Lupus

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Chapter 5 Epigenetics of Lupus Nan Shen, Dong Liang, Yuajia Tang, Yuting Qin For a long time, genetic variation has been thought to be the primary cause of systemic lupus…

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Adjunctive and Preventive Measures

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Chapter 52 Adjunctive and Preventive Measures Diane L. Kamen An improved ability to diagnose and treat systemic lupus erythematosus (SLE) has contributed to longer survival for patients and an increased…

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Autoantibodies

Sep 1, 2016 by in RHEUMATOLOGY Comments Off on Autoantibodies

Chapter 20 Autoantibodies PART AAntibody Structure, Function, and Production Jessica Manson Under normal circumstances, the immune system is involved in host defense. A loss of self-tolerance leads to the development…

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Gastrointestinal and Hepatic Manifestations

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Chapter 33 Gastrointestinal and Hepatic Manifestations David S. Hallegua, Swamy Venuturupalli Gastrointestinal Involvement Gastrointestinal (GI) manifestations are common in patients with systemic lupus erythematosus (SLE), and the prevalence of their…

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Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in SLE

Sep 1, 2016 by in RHEUMATOLOGY Comments Off on Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in SLE

Chapter 43 Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Clinical Laboratory Tests in SLE Francisco P. Quismorio, Jr., Karina D. Torralba One hallmark of systemic lupus erythematosus…

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T Cells

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Chapter 9 T Cells José C. Crispín, George C. Tsokos T cells are central regulators of the immune response through their actions on lymphoid and myeloid cells. By expressing membrane-bound…

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