Cell Pathogenic effects Fibroblasts Produce collagen and other extracellular matrix molecules Adipocytes, endothelial cells, epithelial cells Undergo transition to myofibroblasts expressing a smooth actin and producing collagen T cells Are…
Fig. 3.1 OA pathophysiology. The pathophysiology of OA involves a variety of systemic and local factors, including trauma, aging, obesity, epigenetic, and genetic factors. Chronic inflammation plays a strong role,…
Fig. 8.1 The current design of the mobile-bearing Oxford, marketed as the Oxford Twin Peg Partial Knee, was initially introduced in 2003 in the United Kingdom and later implemented worldwide….
Fig. 9.1 Anteroposterior, lateral, and patellar view of a 66-year-old patient with left knee pain that is recalcitrant to nonoperative measures. There is lateral joint space narrowing, preserved medial compartment,…
Fig. 11.1 Preoperative radiographs of the left knee including (a) standing AP, (b) standing flexion 45-degree PA, (c) lateral and (d) sunrise views. These radiographs demonstrate degenerative changes including medial…
Fig. 3.1 Intraoperative photo of a unicondylar arthroplasty Fig. 3.2 Example of current unicompartmental knee arthroplasty design [2] Age Traditional criterion for UKA includes age over 60 years old. With the…
Fig. 1.1 (MacIntosh tibial insert ) [17]. (MacIntosh tibial insert thicknesses ) [17] Fig. 1.2 (a) St. Georg sled in the all-polyethylene tibia version ; (b) Additional version of the…
Fig. 7.1 Preoperative radiographs of case example demonstrating bone-on-bone medial compartment arthritis on the AP, maintained posteromedial tibial plateau on the lateral, and maintained joint space between the lateral facet…
Fig. 17.1 Well-positioned lateral unicompartmental arthroplasty Given the relative prevalence of isolated medial versus lateral compartment osteoarthritis, medial UKA is much more common than lateral UKA [8, 16, 17]. Overall,…
