Biologics in Sports Medicine—Introduction
Abstract The use of biologics in sports medicine has increased over the years, as the available research shows their potential to increase healing rates and improve outcomes. This chapter presents…
Allograft Tissue Safety and Technology
Abstract Allograft tissues are commonly used by orthopedic surgeons and are processed using a variety of technologies to increase safety and clinical use. For safety, although disease transmission is a…
Growth Factors
Abstract The use of growth factors and platelet-rich plasma (PRP) in orthopedic surgery is a rapidly expanding area of research with a wide array of possible clinical applications. PRP and…
FDA Regulations and Their Impact
Abstract Progress of biologics in orthopaedic surgery faces a delicate balance of clinical application and technology development in the face of government regulations. While early development of orthobiologics was in…
The Role of Orthobiologics in Orthopaedics
Abstract: Orthobiologics have emerged as a new class of substances that allow for novel ways of treating many orthopedic diseases by harnessing or mimicking natural growth factors found within the…
SURGICAL APPROACHES FOR OSTEOCHONDRAL REPAIR AND POSTOPERATIVE IMAGING CONSIDERATIONS
Articular cartilage is a highly specialized tissue with complex ultrastructure and unique biomechanical properties providing for load distribution and a low-friction weight-bearing surface essential for normal pain-free movement of synovial…
ULTRASOUND EVALUATION OF RHEUMATOID ARTHRITIS
In this chapter we focus on the application of ultrasound imaging for the assessment of rheumatoid arthritis (RA), both as a means of identifying structural joint changes (e.g., joint erosions,…
CLINICAL MRI OF OSTEOARTHRITIS AND OSTEOCHONDRAL INJURY
As discussed in Chapter 2 , the structural integrity and function of cartilage and underlying bone are intimately coupled. Chondral injury leads to increased stress on subchondral bone, and, conversely,…
TECHNICAL CONSIDERATIONS FOR CLINICAL MRI OF ARTHRITIS
Inflammatory and noninflammatory arthropathies are a common cause of disability in modern society. MRI offers a noninvasive means of assessing the degree of damage to ligaments, muscle, bone, and articular…
NEW MRI TECHNIQUES FOR OSTEOARTHRITIS
Cartilage Morphometry and Spoiled Gradient-Recalled-Echo, Driven Equilibrium Fourier Transform, Steady-State, High-Field, Phase-Sensitive, and Forward-Looking/Experimental MRI Methods Garry E. Gold Articular cartilage pathology may be the result of degeneration or acute injury….
