Measles (Rubeola)
Measles (Rubeola) Andreea C. Cazacu Gail J. Demmler Infection with measles virus produces an illness characterized by a prodrome of fever, coryza, cough, conjunctivitis, an enanthem (Koplik spots), and development…
Rubella (German Measles)
Rubella (German Measles) Andreea C. Cazacu Gail J. Demmler Rubella is an acute infectious disease characterized by low-grade fever, erythematous maculopapular rash, and adenopathy. Rubella infection in early pregnancy may…
Acquired Cytomegaloviral Infections
Acquired Cytomegaloviral Infections Stuart P. Adler Of all the viruses that infect humans, cytomegalovirus (CMV), a member of the herpes family of viruses, has the largest size genome, with approximately…
Varicella-Zoster Virus Infections
Varicella-Zoster Virus Infections Charles F. Grose Chickenpox is the common childhood exanthem caused by the human herpesvirus varicella-zoster virus (VZV). Before varicella vaccine was recommended for all susceptible children in…
Human Herpesvirus Types 7 and 8
Human Herpesvirus Types 7 and 8 Charles F. Grose HUMAN HERPESVIRUS TYPE 7 In 1990, the discovery of a new herpesvirus was reported. Human herpesvirus (HHV) type 7 was isolated…
Human Herpesvirus Type 6
Human Herpesvirus Type 6 Julia A. McMillan Charles F. Grose Human herpesvirus type 6 (HHV-6) was first isolated in 1986 from the white blood cells of adult patients with lymphoproliferative…
Postnatal Herpes Simplex Virus
Postnatal Herpes Simplex Virus Steve Kohl Herpes simplex virus (HSV) is a moderately large virus consisting of an icosahedral capsid enclosing a core of double-stranded DNA and protein, surrounded by…
Epstein-Barr Virus Infection in Children
Epstein-Barr Virus Infection in Children Katherine Luzuriaga John L. Sullivan In 1964, Anthony Epstein and Yvonne Barr isolated a new herpesvirus from Burkitt lymphoma tumor cells. This herpesvirus (the fifth…
Nonpolio Enteroviruses and Parechoviruses
Nonpolio Enteroviruses and Parechoviruses James D. Cherry The nonpolio enteroviruses and parechoviruses (coxsackieviruses, echoviruses, enteroviruses, and parechoviruses) are responsible for significant and frequent human illness with protean clinical manifestations. These…
