Osteosarcoma in the Elderly: Clinical Features and Outcome
Study Age Total number (secondary/%) Number of Paget’s disease of bone Huvos [5] 60< 117 (66/56 %) 58 (50 %) Grimer [11] 40< 481 (83a/17 %) 42 (8.7 %) Longhi [16] 65< 43 (14/33 %)…
Biological Reconstruction for Extremity Osteosarcoma: Liquid Nitrogen-Treated Tumor-Bearing Bone Graft
Fig. 15.1 Pedicle freezing method. (a) Malignant bone tumor located in proximal femur. (b) Chevron osteotomy was set proximal to the bone lesion, and tumor was carefully curetted outside the…
Long-Term Outcomes and Quality of Life (QOL) in Survivors of Pediatric and Adolescent Osteosarcoma
Fig. 20.1 QOL in survivors of pediatric osteosarcoma; various aspects and factors are involved in the QOL of long-term survivors of osteosarcoma. For QOL assessment, individual factors must be examined…
Genetics of Osteosarcoma
Reference [12] [13] No. of samples 34 primary tumors 10 primary tumors Type of samples Whole-genome sequencing Whole-exome sequencing Total number of mutation/tumor 1483.1 NA No. of mutations in exon…
Treatment of Osteosarcoma Patients with Pulmonary Metastasis
Author (year) n Number of nodules 5-year OAS (%) P 5-year EFS (%) P Kager (2003) 122 1 67 <.001 55 <.001 2–5 24 19 6 – 19 2 Hawkins…
Limb-Salvage Surgery and Reconstruction for Skeletally Immature Childhood Osteosarcoma: Extendible Endoprosthesis
Fig. 10.1 Regression plot between limb length discrepancy and functional score. There was a significant negative correlation between these parameters with an r-value of 0.53 and p = 0.0091 (Quotation from Futani…
Immunotherapy for Osteosarcoma
PBF status* Number Negative Low High Bone tumors Osteosarcoma Primary lesion 83 7 27 49 Lung metastatic lesion 8 1 2 5 Chondrosarcoma 5 2 0 3 Malignant…
Prognostic Factors for Osteosarcoma Patients
Factors Clinical factors Metastatic disease at presentation Patients who have metastases at the time of presentation indicative of a poor prognosis Tumor necrosis after chemotherapy Good response to chemotherapy (>90 %…
Ablation and Cementation Technologies
Fig. 18.1 66-year-old male with L1 compression fracture. (a) Sagittal CT and (b) sagittal STIR MRI demonstrating compression deformity with high T2 signal in L1 compatible with bone edema and…
Metastatic Bone Disease: Humerus and Scapula
Fig. 27.1 Panels a–c: 65-year-old male patient with a metastatic adenocarcinoma lesion and associated pathologic fracture of the humeral diaphysis managed non-operatively. Images of the fracture at presentation (a), 6…
