Genetics of Osteosarcoma
Reference [12] [13] No. of samples 34 primary tumors 10 primary tumors Type of samples Whole-genome sequencing Whole-exome sequencing Total number of mutation/tumor 1483.1 NA No. of mutations in exon…
Treatment of Osteosarcoma Patients with Pulmonary Metastasis
Author (year) n Number of nodules 5-year OAS (%) P 5-year EFS (%) P Kager (2003) 122 1 67 <.001 55 <.001 2–5 24 19 6 – 19 2 Hawkins…
Limb-Salvage Surgery and Reconstruction for Skeletally Immature Childhood Osteosarcoma: Extendible Endoprosthesis
Fig. 10.1 Regression plot between limb length discrepancy and functional score. There was a significant negative correlation between these parameters with an r-value of 0.53 and p = 0.0091 (Quotation from Futani…
Immunotherapy for Osteosarcoma
PBF status* Number Negative Low High Bone tumors Osteosarcoma Primary lesion 83 7 27 49 Lung metastatic lesion 8 1 2 5 Chondrosarcoma 5 2 0 3 Malignant…
Prognostic Factors for Osteosarcoma Patients
Factors Clinical factors Metastatic disease at presentation Patients who have metastases at the time of presentation indicative of a poor prognosis Tumor necrosis after chemotherapy Good response to chemotherapy (>90 %…
Ablation and Cementation Technologies
Fig. 18.1 66-year-old male with L1 compression fracture. (a) Sagittal CT and (b) sagittal STIR MRI demonstrating compression deformity with high T2 signal in L1 compatible with bone edema and…
Metastatic Bone Disease: Humerus and Scapula
Fig. 27.1 Panels a–c: 65-year-old male patient with a metastatic adenocarcinoma lesion and associated pathologic fracture of the humeral diaphysis managed non-operatively. Images of the fracture at presentation (a), 6…
Metastatic Bone Disease: Spine
Histology Percentage of all histologies in patients with spine metastases By histology, percentage of patients with vertebral metastases on bone scintigraphy Breast 26 60 Lung 12 43 Prostate 8 60…
Metastatic Bone Disease: Foot
Fig. 26.1 Sixty-eight year-old female with history of endometrial carcinoma. Lateral radiograph of the right foot demonstrating and aggressive appearing lytic lesion involving the body of the calcaneus Fig. 26.2…
Role of Surgery in Oligometastatic Disease
Primary Patients Solitary (%) Solitary survival (months) Multiple survival (months) En Bloc resection (%) En Bloc survival (months) Other surg. survival (months) Breast 307 10.4 35a 12 3.9 17 13…
