Trial Design and Collaborative Work in Pediatric Rheumatology
Fig. 6.1 An example of a trial with withdrawal design. In part I, patients are treated in an open-label fashion with the experimental therapy. In part II, only responders to…
Epidemiology of Pediatric Rheumatic Diseases
Publication year Reference Authors District Case ascertainment JIA etc. Max (years) Prev. cases Prev per 100,000 Prev 95 % C.I. A.I.* per 100,000 1992 [3] Andersson Gare and Fasth Southwest…
Tips and Pearls for PNF and Collagenase: A Ten-Year Personal Experience
Fig. 21.1 The area of maximum bowstringing is the best location for PNF portals and for collagenase injection. (a) Pre-PNF, (b) post-PNF, (c) pre-CCH, (d) post-CCH 21.2 Technique: Percutaneous Needle…
The Next Stage of Clinical Dupuytren Research: Biomarkers and Chronic Disease Research Tools
Fig. 51.1 Current procedure options for Dupuytren contracture. Recommendations are based on the physician’s qualitative assessment of both the severity of contracture and the biologic severity of disease. This shows…
Contraction Versus Contracture: Considerations on the Pathogenesis of Dupuytren Disease
Fig. 9.1 Normal palmar aponeurosis. (a) Transverse section palmar aponeurosis. The skin is on the left side. Collagen fiber bundles ascend to the skin between fat lobules forming a three-dimensional…
Comparative Effectiveness of Collagenase Injection for Dupuytren Contracture
Fig. 35.1 Patient selection flowchart. CCH clostridium collagenase histolyticum, LF limited fasciectomy, MHQ Michigan Hand Outcomes Questionnaire Table 35.1 shows the baseline characteristics of the study sample before and after…
Controversy: The Contracture in Dupuytren Disease Is a Passive Process
Fig. 11.1 Active versus passive contracture concepts. Comparison of active and passive contracture concepts. The blue lines represent fascia and connective tissues in two hypothetical models of Dupuytren contracture. The…
International Patient Survey (Part 2: Ledderhose Disease)
Country N Country N USA 471 UK 163 Canada 46 Ireland 10 Australia 36 France 7 Germany 190 Other Europe 26 Holland 14 Africa 8 Austria 11 Rest of the…
Minimally Invasive Treatment of Dupuytren Contracture: Collagenase Versus PNF
PNF collagenase Patients 48 23 25 Male: female 39:9 19:4 20:5 Age 69 72 (54–80) 67 (49–79) Right: left hand 27:21 11:12 16:9 Table 34.2 Patients at 24 months…
Preliminary Soft-Tissue Distraction with the Digit WidgetTM in the Management of Advanced Dupuytren Contracture at the Proximal Interphalangeal Joint
Fig. 38.1 Placement of the Digit WidgetTM. The Digit WidgetTM is placed on the dorsal mid-longitudinal axis. Placement under fluoroscopy assures the device is placed in good position and that…
