Musculoskeletal Key

Technique/action With implementation Without implementation or against rival procedure Comments Sensitivity (%) Specificity (%) Sensitivity (%) Specificity (%) Withholding antibiotic prior to sampling >2 weeks [10] 76.9 N/a 41.2 N/a …

Major criteria 1. Two positive periprosthetic (tissue or fluid) cultures with matching organisms 2. A sinus tract communicating with the joint Minor criteria 1. Having three of the following five minor criteria: (a) Increased…

MSIS definition of PJI  PJI exists when: 1. There is a sinus tract communicating with the prosthesis 2. A pathogen is isolated by culture from two or more separate tissue…

© Springer International Publishing AG 2018E. Carlos Rodríguez-Merchán and Sam Oussedik (eds.)The Infected Total Knee Arthroplastyhttps://doi.org/10.1007/978-3-319-66730-0_4 4. Depilation and Skin Preparation to Prevent an Infected Total Knee Arthroplasty Carlos Kalbakdij-Sánchez1  , Gregorio Arroyo-Salcedo1   and E. Carlos Rodríguez-Merchán1   (1) Department of…

Crowe et al. [37] Optimization of modifiable risk factors such as Staphylococcus aureus colonization, and tobacco use prior to primary TKA may decrease the incidence of PJI after primary TKA…

© Springer International Publishing AG 2018E. Carlos Rodríguez-Merchán and Sam Oussedik (eds.)The Infected Total Knee Arthroplastyhttps://doi.org/10.1007/978-3-319-66730-0_3 3. Preoperative Optimization to Prevent an Infected Total Knee Arthroplasty: Host Factors Sven E. Putnis1 and Sam Oussedik2   (1) Specialist Registrar, University…

© Springer International Publishing AG 2018E. Carlos Rodríguez-Merchán and Sam Oussedik (eds.)The Infected Total Knee Arthroplastyhttps://doi.org/10.1007/978-3-319-66730-0_2 2. Microbiological Concepts of the Infected Total Knee Arthroplasty E. Carlos Rodríguez-Merchán1   and Alexander D. Liddle2   (1) Department of Orthopaedic Surgery, “La Paz”…

© Springer International Publishing AG 2018E. Carlos Rodríguez-Merchán and Sam Oussedik (eds.)The Infected Total Knee Arthroplastyhttps://doi.org/10.1007/978-3-319-66730-0_6 6. Preoperative Screening and Eradication of Infection Alexander D. Liddle1   and E. Carlos Rodríguez-Merchán2   (1) University College London Institute of Orthopaedics and Musculoskeletal…

Antimicrobial Recommended dose Cefazolin 2 g (3 g for patients over 120 kg) Cefotaxime 1.5 g Ceftriaxone 2 g Ciprofloxacin 400 mg Clindamycin 900 mg Gentamicin 5 mg/kg Levofloxacin 500…