Staging, Workup, and Surveillance
4 Staging, Workup, and Surveillance Jocelyn Depathy and Stephan Ariyan Epidemiologic studies of malignant melanoma have shown a steady rise in the incidence of this disease in various…
Spitz Nevus, Spitzoid Melanoma, and Atypical Spitzoid Neoplasm
3 Spitz Nevus, Spitzoid Melanoma, and Atypical Spitzoid Neoplasm Rossitza Lazova In 1948, Sophie Spitz, a pathologist from Memorial Hospital in New York City, described the melanoma of…
Alternative Therapies: Regional Chemotherapy for Malignant Melanoma
12 Alternative Therapies: Regional Chemotherapy for Malignant Melanoma Danielle M. Bello and Charlotte E. Ariyan INTRODUCTION Half of all patients with cutaneous melanoma have their primary lesion located…
Surgical Management—Lentigo Maligna and Invasive Melanoma
5 Surgical Management—Lentigo Maligna and Invasive Melanoma Samuel Kim, Stephan Ariyan, and Deepak Narayan LENTIGO MALIGNA Introduction Lentigo maligna (LM), otherwise known as Hutchinson’s melanotic freckle, is a…
Special Sites
6 Special Sites Sarah Persing and Deepak Narayan INTRODUCTION Melanocytes are derived from the neural crest and are widely distributed throughout cutaneous and various mucosal sites. Although melanomas…
Lymph Node Dissection
8 Lymph Node Dissection Daniel C. Thomas and Dale Han INDICATIONS Lymphadenectomy is indicated for the treatment of macroscopic or microscopic melanoma metastatic to associated nodal basin draining…
