Musculoskeletal Key

14 Treating Relapsing Forms of Multiple Sclerosis: Infusion Therapies Jenny J. Feng and Daniel Ontaneda KEY POINTS FOR CLINICIANS        •  There are six infusion therapies for the treatment of relapsing forms…

21 Cognitive Dysfunction in Multiple Sclerosis Stephen M. Rao KEY POINTS FOR CLINICIANS        Cognitive dysfunction …        •  Occurs in 43% to 65% of patients with multiple sclerosis (MS)        •  Is often under…

16 Emerging Therapies Michael D. Kornberg and Peter A. Calabresi KEY POINTS FOR CLINICIANS        •  Current disease-modifying therapies target the peripheral immune system with a primary goal of preventing relapses.        •  The…

PART V. SPECIAL ISSUES   33 Pediatric Multiple Sclerosis Amy T. Waldman KEY POINTS FOR CLINICIANS        •  Pediatric and adult multiple sclerosis (MS) have similar clinical symptoms.        •  The presence of encephalopathy…

PART IV. REHABILITATION AND SYMPTOM MANAGEMENT   17 Overview of Rehabilitation in Multiple Sclerosis Francois Bethoux   KEY POINTS FOR CLINICIANS        •  Rehabilitation refers to a variety of interventions that aim…

13 Treating Relapsing Forms of Multiple Sclerosis: Injection and Oral Therapies Le H. Hua KEY POINTS FOR CLINICIANS        •  There are currently 15 approved disease-modifying therapies for multiple sclerosis (MS).        •  The…

PART III. TREATMENT   2018 American Academy of Neurology Guidelines for Multiple Sclerosis Disease-Modifying Therapy Alexander D. Rae-Grant In April 2018, the American Academy of Neurology (AAN) published a systematic…

2 Overview of Multiple Sclerosis Alexander D. Rae-Grant and Robert J. Fox KEY POINTS FOR CLINICIANS        •  Multiple sclerosis (MS) is a continuously active disease with subclinical lesions occurring 5 to…

224 Epidemiology and Natural History of Multiple Sclerosis Marcus W. Koch KEY POINTS FOR CLINICIANS        •  The incidence and prevalence of multiple sclerosis (MS) varies between different geographical regions and ethnicities….