Osteosarcoma (Continued)
Histologic features consist of mature trabeculae with a peculiar pattern of cement lines similar to that seen in Paget disease of bone. Enmeshed in a low-grade stroma, the trabeculae often…
Osteosarcoma (Continued)
Results of staging studies reflect the tumor’s aggressive nature. Bone scans show intense radioisotope uptake and reveal metastatic lesions to other bones. MRI provides more detailed information about intraosseous involvement,…
Osteosarcoma
Osteosarcoma usually develops in adolescents and affects males slightly more often than females. Although the lesion may occur throughout the skeleton, in 50% of patients it occurs in the region…
Giant Cell Tumor of Bone
Diagnostic Studies. Radiographs reveal a large radiolucent lesion surrounded by a distinct margin of reactive bone. Cortical thinning, endosteal erosion, and trabecularization, or bony septation, of the cavity are associated…
Simple Bone Cyst
Active cysts usually develop in patients younger than 10 years of age. Typically, the cyst abuts the growth plate and occupies most of the metaphysis; it is expansile with a…
Aneurysmal Bone Cyst
Diagnostic Studies. A radiolucent lesion with a ballooned expansion of the bone cortices (“finger in balloon”) is the radiographic hallmark of an aneurysmal bone cyst. Although some lesions appear to…
Eosinophilic Granuloma
Eosinophilic granuloma usually occurs as a solitary, symptomatic lesion in children younger than 20 years of age but can occur as multiple tumors at any age and at any site….
Nonossifying Fibroma and Desmoplastic Fibroma
Diagnostic Studies. The lesion commonly develops in the metaphysis of the distal femur or distal tibia and is eccentrically located, usually within or adjacent to the cortex. Radiographs reveal a…
Fibrous Dysplasia
Monostotic lesions generally occur in the proximal femur, proximal tibia, mandible, and ribs. Polyostotic disease, which usually presents earlier, may be unilateral or widespread, affecting long bones, hands, feet, facial…
Chondroblastoma and Chondromyxoid Fibroma
Diagnostic Studies. The radiographic hallmark is an epiphyseal radiolucent lesion with fine punctate calcifications suggestive of a cartilaginous lesion. The tumor is usually bordered by a well-defined margin of reactive…
