Autoimmune Encephalitis
41 Autoimmune Encephalitis Michel Toledano KEY POINTS FOR CLINICIANS • Autoimmune encephalitis (AE) describes a group of disorders associated with neural-specific autoantibodies. • Antibodies can target either intracellular antigens or extracellular plasma…
Magnetic Resonance Imaging in Multiple Sclerosis
8 Magnetic Resonance Imaging in Multiple Sclerosis Christopher J. Karakasis, Aliye O. Bricker, and Stephen E. Jones KEY POINTS FOR CLINICIANS • MRI remains a mainstay for diagnosis and disease monitoring…
Multiple Sclerosis Genetics
5 Multiple Sclerosis Genetics Bruce A. C. Cree KEY POINTS FOR CLINICIANS • Family aggregation and twin studies indicate that heredity contributes to multiple sclerosis (MS) risk. • The primary MS susceptibility…
Acute Disseminated Encephalomyelitis
39 Acute Disseminated Encephalomyelitis Eliza Gordon-Lipkin and Brenda Banwell KEY POINTS FOR CLINICIANS • Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder of the central nervous system that manifests as…
Eye Symptoms, Signs, and Therapy in Multiple Sclerosis
23 Eye Symptoms, Signs, and Therapy in Multiple Sclerosis Collin M. McClelland and Steven L. Galetta KEY POINTS FOR CLINICIANS • Demyelinating optic neuritis (DON) is a hallmark manifestation of multiple…
