Antiphospholipid Syndrome

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Antiphospholipid Syndrome

The antiphospholipid syndrome (APS) is an autoimmune multisystem disease characterized by thromboembolic events, pregnancy morbidity, hematological, dermatological, neurological, and other manifestations in the presence of elevated titers of antiphospholipid antibodies…

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Uveitis in Juvenile Idiopathic Arthritis

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Uveitis in Juvenile Idiopathic Arthritis

Inflammatory eye diseases comprise some of the most devastating complications of childhood rheumatic diseases, especially juvenile idiopathic arthritis (JIA). Chronic (initially asymptomatic) uveitis accompanying JIA is one of the most…

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Localized Scleroderma

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Localized Scleroderma

Scleroderma refers to hard skin that develops because of an excessive accumulation of collagen. In the localized form (localized scleroderma [LS], also called morphea ), inflammation in the skin and…

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Juvenile Psoriatic Arthritis

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Juvenile Psoriatic Arthritis

The association of arthritis with psoriasis was described almost 200 years ago, but it was not reported in children until the 1950s. Juvenile psoriatic arthritis (JPsA) is a heterogeneous entity,…

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Arthropathies of Inflammatory Bowel Disease

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Arthropathies of Inflammatory Bowel Disease

Definition and Classification The arthropathies of inflammatory bowel disease (IBD) may be defined as any noninfectious arthritis occurring before or during the course of Crohn’s disease (CD), indeterminate colitis (IC),…

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Polyarticular Juvenile Idiopathic Arthritis

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Polyarticular Juvenile Idiopathic Arthritis

Definitions Chronic childhood arthritis affecting five joints or more during the first 6 months of disease is defined as polyarthritis. The International League of Associations for Rheumatology (ILAR) classification system…

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Laboratory Investigations

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Laboratory Investigations

Introduction Over the past 80 years, the role of laboratory investigation in rheumatic diseases has progressed from reports of curious in vitro phenomena in diseases defined purely on clinical grounds…

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Sjögren Syndrome

Jun 30, 2019 by in RHEUMATOLOGY Comments Off on Sjögren Syndrome

The syndrome of chronic inflammation of the exocrine glands, principally the salivary and lacrimal glands, was first described by Henrik Sjögren, a Swedish ophthalmologist, who published in 1933 the first…

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