Chapter 9B Autologous Chondrocyte Implantation Quality Assurance of Cells for Chondrogenic Implantation Stephen J. Duguay Introduction High-quality chondrocytes are essential for successful autologous chondrocyte implantation (ACI) outcomes. Cell therapy manufacturers…
Chapter 9A Cartilage Biopsy Handling Anders Lindahl, Sebastian Concaro Cartilage Biopsy and Handling The technology of autologous chondrocyte transplantation is based on the use of autologous cartilage for cell processing….
Chapter 4C Bone Marrow Stimulating Techniques Autologous Matrix-Induced Chondrogenesis (AMIC) Peter Behrens, J.P. Benthien Introduction Chondral and osteochondral defects may affect any major joint, but they more often affect the…
Chapter 2 Patient Evaluation and Treatment Algorithms Marco Delcogliano, Jason Boyer, Bert R. Mandelbaum Introduction The clinical consequences of articular cartilage defects of the knee are pain, swelling, mechanical symptoms,…
Chapter 16 Postoperative Cartilage Repair Rehabilitation Holly J. Silvers, Karen Hambly Introduction Participation in physical activity is at the forefront of international health promotion agendas, and there is increasing encouragement…
Chapter 1 Cartilage Morphology Mats Brittberg Hyaline cartilage provides the diarthrodial joint with a low-friction surface, resilience, and compressive stiffness, and this unique tissue is, under normal conditions, wear resistant….
16 Osteochondral Allograft Transplantation WILLIAM D. BUGBEE AND MICHAEL J. OSTEMPOWSKI Experience with fresh osteochondral allografting in the management of chondral and osteochondral injuries extends over many decades. In fact,…
15 Autologous Chondrocyte Implantation JEFFREY W. WILEY, TIM BRYANT, AND TOM MINAS Full-thickness chondral lesions in the knee have been known to be problematic for over two centuries.1 The incidence…
17 Osteochondral Lesions of the Talus MARK E. EASLEY, STEVEN D. SIDES, AND ALISON P. TOTH Treatment of symptomatic focal talar osteochondral defects has undergone a dramatic evolution over the…
19 Osteochondral Defects in the Elbow RUSSELL S. PETRIE AND JAMES P. BRADLEY Treatment of articular cartilage injuries remains difficult and frustrating in virtually every joint in which these maladies…
