Th17 Cells: Differentiation and Regulation
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 3.1 Identification of Th17 Cells The increased IL-17A production by CD4+ T cells from T…
Overview of IL-17 Family
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 1.1 Discovery and Structure of IL-17 The name of IL-17 was first proposed by Yao…
Therapeutic Applications: Strategies and Molecules Targeting the IL-17/Th17 Pathway
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA As shown in Fig. 5.1a–e, there are multiple points where the interleukin 17 (IL-17)/Th17 pathway…
Concluding Remarks
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA The family of IL-17 cytokines is one of the most ancient cytokines that plays an…
IL-17 in Host Defense
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 2.1 Cellular Source of IL-17 Many cell types including immune and nonimmune cells are able…
The Role of IL-17/Th17 Pathway in the Pathogenesis of Autoimmune Inflammatory Diseases
(1) VA Portland Health Care System, Oregon Health & Science University, Portland, Oregon, USA 4.1 Rheumatoid Arthritis Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium and…
