Musculoskeletal Key

Protocol Histological response EFS OS POG-8651 Viable tumor <10 % (n = 26) 5 years 73 % ± 8 % 5 years 77 % ± 9 % Viable tumor ≧10 % (n = 16) 44 % ± 15 80 % ± 12 % CCG-782 Viable tumor <5 % 8 years 81 % 8…

Fig 8.1 OOS-D regimen Complete blood count (CBC) and renal and hepatic functions were monitored before and after each chemotherapy administration. Granulocyte colony-stimulating factor was given to patients with grade…

Study Age Total number (secondary/%) Number of Paget’s disease of bone Huvos [5] 60< 117 (66/56 %) 58 (50 %) Grimer [11] 40< 481 (83a/17 %) 42 (8.7 %) Longhi [16] 65< 43 (14/33 %)…

Fig. 15.1 Pedicle freezing method. (a) Malignant bone tumor located in proximal femur. (b) Chevron osteotomy was set proximal to the bone lesion, and tumor was carefully curetted outside the…

Fig. 20.1 QOL in survivors of pediatric osteosarcoma; various aspects and factors are involved in the QOL of long-term survivors of osteosarcoma. For QOL assessment, individual factors must be examined…

Reference [12] [13] No. of samples 34 primary tumors 10 primary tumors Type of samples Whole-genome sequencing Whole-exome sequencing Total number of mutation/tumor 1483.1 NA No. of mutations in exon…

Fig. 10.1 Regression plot between limb length discrepancy and functional score. There was a significant negative correlation between these parameters with an r-value of 0.53 and p = 0.0091 (Quotation from Futani…

  PBF status*   Number Negative Low High Bone tumors Osteosarcoma      Primary lesion 83 7 27 49  Lung metastatic lesion 8 1 2 5 Chondrosarcoma 5 2 0 3 Malignant…