Coeliac Disease in Elderly Patients
CD forms Classic Silent Latent Potential Subclinical Symptoms + (+RA)/− − Often – Atypical Biopsy + + ↑IEL ↑IEL/− + Serology + + + ± + +RA positive family history,…
Alkaptonuria and Ochronosis
Fig. 19.1 Pigmented patches in the sclera typical of alkaptonuric ochronosis The diagnosis of alkaptonuria is based on the characteristic findings in urine. Alkaptonuria patients do not seek medical help…
Metabolic Osteopathy in Late-Onset Celiac Disease
Fig. 20.1 Case study 1. Bone densitometry demonstrates skeletal demineralization with L-spine BMD value of 0.910 g/cm2 and T-score −2.4, femoral neck BMD value of 0.819 g/cm2 and T-score −0.8,…
Neck and Shoulder Pain
Fig. 26.1 Cutaneous radiation of pain during irritation of individual structures. (a) Radiation of pain during irritation of intervertebral discs (Modified after Cloward); (b) radiation of pain during irritation of…
Clinical Syndromology of Gouty Arthritis
Fig. 17.1 Polyarticular tophaceous gout. (a) Palmar view. (b) Dorsal view Frequency of polyarticular involvement in the elderly is probably the result of multiple factors. Chronic hyperuricemia may be induced…
Diffuse Idiopathic Skeletal Hyperostosis
Calcification and ossification along the anterolateral aspect of at least four consecutive vertebral bodies Preservation of the intervertebral disc space Absence of SI joint ankylosis and SI erosion/sclerosis DISH affects…
Haemochromatosis Arthropathy
Type Form Mutated gene Location Heredity 1 Adult HFE (high Fe) 6p21.3 ARa 2A Juvenile RGMc/HJV (hemojuvelin) 1q21.1 ARa 2B Juvenile HAMP (hepcidin antimicrobial peptide) 19q13.1 ARa 3 Adult TFR2…
Paget’s Disease of Bone
Fig. 33.1 Clinical symptoms of Paget’s disease shown by imaging methods. (a) Female patient with more than 20-year history of untreated disease. Significant skull bone changes and complete loss of…
Relapsing Polychondritis
Fig. 10.1 Red and swollen auricles tender to palpation in relapsing polychondritis 10.5 Arthropathy in Relapsing Polychondritis RP quite often involves joints usually independently of other manifestations. The clinical features…
