Biologics in Musculoskeletal Oncology
Abstract Biologics serve a unique role in the management of musculoskeletal oncology. While most of the field of biologics in orthopedic surgery focuses on injury repair, biologics in oncology can…
Biologics in Fracture Care
Abstract Delayed healing and nonunion remain significant clinical issues in fracture care. The field of biologic augmentation (orthobiologics) has been developed to help solve this problem. Orthobiologics rely on the…
Treating the Subchondral Environment and Avascular Necrosis
Abstract The subchondral bone is a key component of the osteochondral unit as it provides mechanical and biological support for the overlying articular cartilage. It has the capability to undergo…
Biologic Augmentation in Peripheral Nerve Repair
Abstract Peripheral nerve injuries are known to have devastating impact on a patient’s quality of life. These injuries can occur after high-impact activities, traumatic injuries, or motor vehicle accidents. When…
Orthobiologics in Osteoarthritis
Abstract Osteoarthritis has emerged as one of the major public health problems with a burden of disease that significantly affects the world’s aging population. Osteoarthritis is a progressive degeneration of…
Biologics in Spinal Fusion
Abstract An estimated 200,000 spinal fusion are performed in the United States on annually for a large range of pathologic conditions. The goal of spinal fusion is to restore or…
Biologics in Hand Surgery
Abstract Hand and upper extremity surgeons have discovered unique roles for biologics in the treatment of their patients. This chapter reviews some of these techniques, including the use of bone…
Regenerative Engineering in the Field of Orthopedic Surgery
Abstract Regenerative engineering seeks to address the most complex and relevant questions in the realm of future of regeneration, namely, how to regenerate complex structures comprised of multiple types of…
Biologic Augmentation in Peripheral Nerve Repair
Abstract Peripheral nerve injuries are known to have devastating impact on a patient’s quality of life. These injuries can occur after high-impact activities, traumatic injuries, or motor vehicle accidents. When…
Bone Loss in the Upper Extremity
Abstract Bone loss in the upper extremity poses a challenging pathology for the orthopaedic surgeon to effectively treat. The goal of treatment when managing upper extremity bone loss is to…
