Fig. 1 Radiographic outcomes in randomized controlled trials with methotrexate-naïve patients. TNF tumor necrosis factor inhibitor, MTX methotrexate, ETA etanercept, IFX infliximab, ADA adalimumab, ERA early rheumatoid arthritis (From Yazici…
and Hasan Yazici2 (1) Division of Rheumatology, Rush University Medical Center, 1611 West Harrison Street, Chicago, IL 60612, USA (2) Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul,…
Fig. 1 Algorithm for setting up a rheumatology research project Create a Multidisciplinary Study Team (i.e., Clinicians, Epidemiologists, Biostatisticians, Ethicists, Patient Representatives, and Others, as Needed) Any rheumatology research is…
Fig. 18.1 Contact stress patterns across the surface of the proximal tibia at 14 % of the gait cycle show that load is distributed across both tibial plateaus but varies…
Fig. 19.1 This cut-through demonstrates a tear within the ACL (long arrow) on a 3D SPGR image (left) and a 2D Fast Spin Echo (FSE) T2 weighted image (right). The…
Fig. 24.1 These radiographs illustrate the tibial plafond fracture severity spectrum. Simple intra-articular fractures result from low energy impacts (left). As energy increases (moving from left to right in the…
Fig. 8.1 Left: illustrates displacement of a lateral tibial plateau fracture model used to assess the effect of displacement on observed contact stresses. Right: shows that greater joint displacement leads…
Fig. 17.1 Blunt impact suppresses cartilage ATP production. Explant cartilage was harvested for ATP assay 24 or 48 h postimpact (7 J/cm2). Cartilage was harvested from control (non-impacted) explants and…
Fig. 9.1 Dynamic human cadaveric ankle loading model in which ankles were made incongruous with a coronally directed osteotomy of the anterior distal tibial surface displaced proximally 2.0 mm (a)….
Fig. 25.1 Framework for PTOA Pathomechanics. Modified from: Andriacchi and Mundermann 2006 [13] Pre-injury biomarker generation. As illustrated in Fig. 25.1, biomarker generation may begin in the pre-injury phase among…
