Abstract Pain is a common presenting and often persistent symptom for children with rheumatological disease. Pain is not clearly related to disease severity in children with inflammatory juvenile idiopathic arthritis,…

Abstract Pediatric granulomatous diseases constitute a heterogenous group of conditions in terms of clinical phenotypes, pathogenic mechanisms, and outcomes. The common link is the presence of multinucleated giant cells in…

Abstract Genetic and genomic investigations are a starting point for the study of human disease, seeking to discover causative variants relevant to disease pathophysiology. Over the past 5 years, massively…

The publisher regrets that the subtitle of this article was omitted in the printed version. The correct full title is: ‘Osteoporosis and fragility fractures: Vertebral fractures’. The publisher would like…

Abstract This review covers the evidence relating to lifestye modification in the big three musculoskeletal conditions: osteoarthritis, osteoporosis and rheumatoid arthritis. Lifestyle is of considerable importance in the first two…

The authors regret that the affiliations of authors Benedicte Neven and Carine H. Wouters were omitted from the previously published version of this article. The affiliations are correct as given…

Abstract With musculoskeletal conditions now identified as the second highest cause of the morbidity-related global burden of disease, models of care for the prevention and management of disability related to…

Abstract It is frequently considered that, for many people, symptomatic osteoarthritis involving the lower limb joints is a largely preventable ‘lifestyle disease’. The purpose of this review is to evaluate…