Abstract The subchondral bone is a key component of the osteochondral unit as it provides mechanical and biological support for the overlying articular cartilage. It has the capability to undergo…
Abstract Peripheral nerve injuries are known to have devastating impact on a patient’s quality of life. These injuries can occur after high-impact activities, traumatic injuries, or motor vehicle accidents. When…
Abstract Osteoarthritis has emerged as one of the major public health problems with a burden of disease that significantly affects the world’s aging population. Osteoarthritis is a progressive degeneration of…
Abstract An estimated 200,000 spinal fusion are performed in the United States on annually for a large range of pathologic conditions. The goal of spinal fusion is to restore or…
Abstract Hand and upper extremity surgeons have discovered unique roles for biologics in the treatment of their patients. This chapter reviews some of these techniques, including the use of bone…
Abstract Regenerative engineering seeks to address the most complex and relevant questions in the realm of future of regeneration, namely, how to regenerate complex structures comprised of multiple types of…
Abstract Peripheral nerve injuries are known to have devastating impact on a patient’s quality of life. These injuries can occur after high-impact activities, traumatic injuries, or motor vehicle accidents. When…
Abstract Bone loss in the upper extremity poses a challenging pathology for the orthopaedic surgeon to effectively treat. The goal of treatment when managing upper extremity bone loss is to…
Abstract The role for Biologics in Foot and Ankle Surgery is an ever-changing landscape. The modern day foot and ankle surgeon must be aware of the biologic agents at their…
Abstract Massive rotator cuff tears are often chronic in presentation and present with many factors that may inhibit successful repair. Retear rate of large-to-massive rotator cuff tears approaches 70% in…
