MUSCULOSKELETAL MEDICINE

Impaired Parathyroid Function and Bone Formation: A Risk for Development of Adynamic Bone Disease to Enhance Vascular Calcification

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Impaired Parathyroid Function and Bone Formation: A Risk for Development of Adynamic Bone Disease to Enhance Vascular Calcification

Glycemic control HbA1C GA Excellent (HbA1C≤6 %, GA≤18 %) 307 (57.1 %) 152 (28.3 %) Good (6 %<HbA1C≤7 %, 18 %<GA≤21 %) 128 (23.7 %) 106 (19.7 %) Good (7 %<HbA1C≤8 %, 21 %<GA≤24 %) 65 (12.1 %) 84 (15.6 %) Poor (8 %<HbA1C, 24 %<GA) 38 (7.1 %)…

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Overview

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Overview

Fig. 9.1 The factors that affect to GLUT4 translocation and glucose utilization in the skeletal muscle The working mechanism of insulin resistance is complex, probably involving numerous factors, including defective…

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Ectopic Fat Accumulation and Glucose Homeostasis: Role of Leptin in Glucose and Lipid Metabolism and Mass Maintenance in Skeletal Muscle

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Ectopic Fat Accumulation and Glucose Homeostasis: Role of Leptin in Glucose and Lipid Metabolism and Mass Maintenance in Skeletal Muscle

Fig. 14.1 Schematic representation of the leptin’s effects on glucose and lipid metabolism in skeletal muscle Recent studies have extended our understanding of the role of leptin in obesity and…

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Sarcopenia in Diabetes Mellitus

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Sarcopenia in Diabetes Mellitus

Fig. 16.1 Interaction between sarcopenia and diabetes. Insulin resistance in skeletal muscle is the most important link between sarcopenia and diabetes. Sarcopenia and obesity appear to have additive effects on…

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Mechanism for the Development of Bone Disease in Diabetes: Increased Oxidative Stress and Advanced Glycation End Products

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Mechanism for the Development of Bone Disease in Diabetes: Increased Oxidative Stress and Advanced Glycation End Products

Fig. 5.1 Effects of the AGE-RAGE axis on osteoblasts 5.5 AGE-RAGE Axis and Osteoclasts There is some controversy about the pathological role of AGEs in osteoclast function in osteoporosis. Miyata…

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Mechanism of Skeletal Muscle Contraction: Intracellular Signaling in Skeletal Muscle Contraction

Jul 3, 2016 by in MUSCULOSKELETAL MEDICINE Comments Off on Mechanism of Skeletal Muscle Contraction: Intracellular Signaling in Skeletal Muscle Contraction

Fig. 10.1 Proposed model of exercise-induced signaling pathway in the skeletal muscle. Classified into three signaling pathways: AMP-activated protein kinase (AMPK), Ca2+, and mitogen-activated protein kinase (MAPK). AMPK is activated…

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