Pathology of Osteoarthritis
Pathology of Osteoarthritis Aubrey J. Hough Jr. Historical Concepts of Osteoarthritis Medical science is to a degree inseparable from its ancient origins in so-called natural philosophy. Disease itself was originally…
Etiopathogenesis of Osteoarthritis
Etiopathogenesis of Osteoarthritis A. Robin Poole Farshid Guilak Steven B. Abramson Osteoarthritis (OA) is a condition that represents a pathological imbalance of degradative and reparative processes involving the whole joint…
Features of Osteoarthritis at Specific Sites
Features of Osteoarthritis at Specific Sites Features of osteoarthritis of the knee The knee is comprised of one synovial cavity with three principle compartments: the medial and lateral tibiofemoral joints,…
Epidemiology of Osteoarthritis
Epidemiology of Osteoarthritis Leena Sharma Dipali Kapoor Introduction Osteoarthritis (OA) is the most common form of arthritis and a leading cause of chronic disability, in large part due to knee…
Subsets of Osteoarthritis
Subsets of Osteoarthritis Generalized osteoarthritis Early epidemiological studies using radiological surveys detailed the fact that many patients had osteoarthritis of multiple joints, suggesting a generalized, in-built predisposition (3.1). Furthermore, the…
Principles of Management
Principles of Management Introduction In the management of osteoarthritis, there are several tools available (5.1). There are a wide number of options, including non-pharmacological, pharmacological, and surgical options, which may…
Introduction
Introduction What is osteoarthritis? The answer to this apparently simple question is an ongoing problem for a condition that is so common. Everyone seems to be able to recognize ‘osteoarthritis’…
General Features of Osteoarthritis
General Features of Osteoarthritis What are the clinical features of osteoarthritis? The clinical features of osteoarthritis relate to both symptoms and signs. As has been discussed in Chapter 1, the…
Management of Osteoporosis
Management of Osteoporosis Introduction Bone loss with ageing is universal and many will become osteoporotic in later life with increased risk of fracture. Measures therefore need to be taken by…
Future Therapeutic Options
Future Therapeutic Options Paul D. Miller Current osteoporosis therapies have been shown to reduce the risk of fragility fractures generally from 50% to 65% over a period of 3 years….
