Corticosteroids in Lupus
Corticosteroids are the mainstay of treatment of systemic lupus erythematosus, with most patients receiving them at some point in the course of their disease. Corticosteroid use is associated with significant…
Glucocorticoids and Rheumatoid Arthritis
Glucocorticoids (GCs) were discovered in the 1940s and were administered for the first time to patients with rheumatoid arthritis in 1948. However, side effects were subsequently reported. In the last…
Corticosteroids
Glucocorticoids are primary stress hormones that regulate a variety of physiologic processes and are essential for life. The actions of glucocorticoids are predominantly mediated through the classic glucocorticoid receptor (GR)….
The History of Cortisone Discovery and Development
Philip Hench, Edward Kendall, and Tadeus Reichstein received the Nobel Prize in medicine and physiology in 1950 for their “investigations of the hormones of the adrenal cortex.” Hench and Kendall…
Corticosteroids: Friends and Foes
Marcy B. Bolster, MD, Editor Corticosteroids have been a mainstay of treatment employed by rheumatologists since the Nobel Prize–winning discovery of cortisone in 1950 by Drs Hench, Kendall, and Reichstein….
Corticosteroids
Michael H. Weisman, MD, Consulting Editor Nowhere is there more controversy in rheumatic diseases than the role of corticosteroids, and that is the reason for the development of this issue….
The Promise of Patient-Reported Outcomes Measurement Information System—Turning Theory into Reality
PROMIS, the Patient-Reported Outcomes Measurement Information System, is opening new possibilities to explore and learn how patient (or proxy) self-report of core symptoms and health-related quality of life can meaningfully…
Challenges and Opportunities in Using Patient-reported Outcomes in Quality Measurement in Rheumatology
Use of patient-reported outcome measures (PROs) in rheumatology research is widespread, but use of PRO data to evaluate the quality of rheumatologic care delivered is less well established. This article…
The Challenge and Opportunity of Capturing Patient Reported Measures of Rheumatoid Arthritis Disease Activity in Vulnerable Populations with Limited Health Literacy and Limited English Proficiency
Limited health literacy and limited English proficiency are widely prevalent and contribute to rheumatoid arthritis (RA) health care disparities. The RA Patient Global Assessment of Disease Activity often introduces complexity…
Using Patient-Reported Outcome Measures to Capture the Patient’s Voice in Research and Care of Juvenile Idiopathic Arthritis
Patient-reported outcome (PRO) measures provide a valuable window into how patients with juvenile idiopathic arthritis and their parents perceive their functioning, quality of life, and medication side effects in the…
